STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07389.1HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR006402:IPR006439:IPR005834; KEGG: mem:Memar_1535 HAD family hydrolase; PFAM: Haloacid dehalogenase-like hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; [...] (229 aa)    
Predicted Functional Partners:
EJG07390.1
KEGG: mem:Memar_1534 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.791
EJG07391.1
KEGG: mem:Memar_1533 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.791
EJG07393.1
ABC-type transporter, integral membrane subunit; PFAM: FecCD transport family; COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: mem:Memar_2330 transport system permease protein; PFAM: Bacterial transport system permease protein; SPTR: Transport system permease protein.
 
     0.681
EJG07388.1
PFAM: Glutaredoxin; COGs: COG0695 Glutaredoxin and related protein; InterPro IPR002109; KEGG: mpi:Mpet_1341 glutaredoxin; PFAM: Glutaredoxin; SPTR: Glutaredoxin.
     
 0.677
EJG07686.1
PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR012269:IPR000425; KEGG: afu:AF1426 glycerol uptake facilitator, MIP channel (GlpF); PFAM: Major intrinsic protein; SPTR: Probable aquaporin AqpM; TIGRFAM: Aquaporin.
   
 
 0.662
EJG08206.1
5'-Nucleotidase domain-containing protein; PFAM: Calcineurin-like phosphoesterase; 5'-nucleotidase, C-terminal domain; COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR008334; KEGG: mem:Memar_1147 5'-nucleotidase domain-containing protein; PFAM: 5'-Nucleotidase, C-terminal; Metallophosphoesterase; SPTR: 5'-Nucleotidase domain protein.
  
 
 0.654
ribL
Cytidyltransferase-related domain protein; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme.
 
 
 0.641
EJG08123.1
PFAM: Glutamine amidotransferase class-I; COGs: COG0518 GMP synthase - Glutamine amidotransferase domain; InterPro IPR000991; KEGG: slp:Slip_2120 glutamine amidotransferase class-I; PFAM: Glutamine amidotransferase class-I, C-terminal; SPTR: GMP synthase.
 
  
  0.640
EJG07387.1
Rubredoxin; PFAM: Ferredoxin thioredoxin reductase catalytic beta chain; COGs: COG4802 Ferredoxin-thioredoxin reductase catalytic subunit; KEGG: mem:Memar_2454 rubredoxin; SPTR: Rubredoxin.
       0.636
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.630
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.