STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07462.1PFAM: Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: mbn:Mboo_1225 precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; SPTR: Precorrin-8X methylmutase CbiC/CobH. (208 aa)    
Predicted Functional Partners:
EJG07460.1
PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2241 Precorrin-6B methylase 1; InterPro IPR012818:IPR000878; KEGG: mem:Memar_0515 cobalt-precorrin-6Y C(5)-methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-6Y C5,15-methyltransferase (Decarboxylating); TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core.
 
 
 0.999
EJG07463.1
precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase; COGs: COG1010 Precorrin-3B methylase; InterPro IPR006363:IPR000878; KEGG: mpi:Mpet_1758 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; manually curated.
  
 0.999
EJG07464.1
Cobalamin (vitamin B12) biosynthesis CbiG protein; PFAM: Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal; COGs: COG2073 Cobalamin biosynthesis protein CbiG; InterPro IPR002750; KEGG: mem:Memar_0511 cobalamin biosynthesis protein CbiG; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiG protein.
 
 
 0.999
EJG07465.1
Precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase; COGs: COG2875 Precorrin-4 methylase; InterPro IPR006362:IPR000878; KEGG: mem:Memar_0510 uroporphyrin-III C/tetrapyrrole methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-4 C11-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core.
 
 
 0.999
EJG07466.1
PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878; KEGG: mpi:Mpet_1755 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
 
 
 0.999
EJG07467.1
Methyltransferase type 11; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR013216; KEGG: mem:Memar_0508 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Methyltransferase type 11; SPTR: Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit.
 
 
 0.999
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
 
 0.998
cbiD
cobalt-precorrin-6A synthase (deacetylating); Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.996
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.996
cobD
Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 
 0.972
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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