STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
mchMethenyltetrahydromethanopterin cyclohydrolase; Catalyzes the reversible interconversion of 5-formyl-H(4)MPT to methenyl-H(4)MPT(+); Belongs to the MCH family. (314 aa)    
Predicted Functional Partners:
ftr
formylmethanofuran/tetrahydromethanopterinN-form yltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
 
 0.999
mtd
F420-dependent methylenetetrahydromethanopterin dehydrogenase; Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.
 
  
 0.994
EJG06472.1
PFAM: Amidohydrolase family; TIGRFAM: formylmethanofuran dehydrogenase subunit A; COGs: COG1229 Formylmethanofuran dehydrogenase subunit A; InterPro IPR012027:IPR013108; KEGG: mem:Memar_0619 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: Formylmethanofuran dehydrogenase, subunit A; TIGRFAM: Formylmethanofuran dehydrogenase, subunit A.
 
   
 0.818
EJG06471.1
PFAM: GXGXG motif; TIGRFAM: formylmethanofuran dehydrogenase subunit C; COGs: COG2218 Formylmethanofuran dehydrogenase subunit C; InterPro IPR017550:IPR002489; KEGG: mem:Memar_0618 formylmethanofuran dehydrogenase; PFAM: Glutamate synthase, alpha subunit, C-terminal; SPTR: Formylmethanofuran dehydrogenase, subunit C; TIGRFAM: Formylmethanofuran dehydrogenase subunit C.
 
   
 0.817
EJG06961.1
PFAM: Amidohydrolase family; TIGRFAM: formylmethanofuran dehydrogenase subunit A; COGs: COG1229 Formylmethanofuran dehydrogenase subunit A; InterPro IPR013108:IPR012027; KEGG: mem:Memar_1188 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: Formylmethanofuran dehydrogenase, subunit A; TIGRFAM: Formylmethanofuran dehydrogenase, subunit A.
 
   
 0.817
EJG06962.1
PFAM: GXGXG motif; TIGRFAM: formylmethanofuran dehydrogenase subunit C; COGs: COG2218 Formylmethanofuran dehydrogenase subunit C; InterPro IPR002489:IPR017550; KEGG: mem:Memar_1189 glutamate synthase alpha subunit; PFAM: Glutamate synthase, alpha subunit, C-terminal; SPTR: Formylmethanofuran dehydrogenase, subunit C; TIGRFAM: Formylmethanofuran dehydrogenase subunit C.
 
   
 0.813
EJG07508.1
Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; Protein of unknown function (DUF98); TIGRFAM: beta-RFAP synthase; COGs: COG1907 sugar kinase; InterPro IPR004422:IPR002800:IPR006204:IPR013750; KEGG: mpi:Mpet_2520 beta-ribofuranosylaminobenzene 5'-phosphate synthase family protein; PFAM: Protein of unknown function DUF98; GHMP kinase; GHMP kinase, C-terminal; SPTR: Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; TIGRFAM: GHMP kinase group 1.
 
     0.807
EJG07635.1
triphosphoribosyl-dephospho-CoA protein; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase; COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR002736; KEGG: mem:Memar_1728 triphosphoribosyl-dephospho-CoA protein; PFAM: Triphosphoribosyl-dephospho-CoA protein; SPTR: Triphosphoribosyl-dephospho-CoA protein.
 
     0.780
EJG07847.1
TIGRFAM: probable H4MPT-linked C1 transfer pathway protein; COGs: COG1548 transcriptional regulator/sugar kinase; InterPro IPR002756; KEGG: mbn:Mboo_0921 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Tetrahydromethanopterin-linked C1 transfer pathway, putative.
 
     0.774
mfnB
UPF0264 protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
 
     0.765
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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