STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07546.1KEGG: mem:Memar_1521 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated. (105 aa)    
Predicted Functional Partners:
EJG07544.1
ATP-grasp fold domain protein, DUF201-type; PFAM: ATP-grasp domain; COGs: COG2232 ATP-dependent carboligase related to biotin carboxylase; InterPro IPR003806; KEGG: mem:Memar_1523 hypothetical protein; PFAM: ATP-grasp fold, DUF201-type; SPTR: Putative uncharacterized protein.
       0.936
EJG07545.1
tRNA ribose 2'-O-methyltransferase aTrm56; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
       0.936
EJG07542.1
Metal dependent phosphohydrolase; PFAM: HD domain; TIGRFAM: TIGR00295 family protein; uncharacterized domain HDIG; InterPro IPR006675:IPR006674:IPR003607; KEGG: mem:Memar_1525 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; SMART: Metal-dependent phosphohydrolase, HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: HDIG.
       0.919
tfe
Transcription factor E; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems [...]
       0.919
EJG07547.1
KEGG: mem:Memar_1520 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.604
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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