STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07567.1PFAM: Radical SAM superfamily; COGs: COG4277 DNA-binding protein with the Helix-hairpin-helix motif; InterPro IPR007197:IPR006638:IPR003583; KEGG: mem:Memar_0388 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; Helix-hairpin-helix DNA-binding motif, class 1; SPTR: Radical SAM domain protein. (345 aa)    
Predicted Functional Partners:
EJG07568.1
Protein of unknown function DUF2148; PFAM: Uncharacterized protein containing a ferredoxin domain (DUF2148); COGs: COG4739 Uncharacterized protein containing a ferredoxin domain; InterPro IPR019224; KEGG: mem:Memar_1081 hypothetical protein; PFAM: Protein of unknown function DUF2148; SPTR: Putative uncharacterized protein.
       0.547
EJG07569.1
GHMP kinase; TIGRFAM: beta-RFAP synthase; COGs: COG1907 sugar kinase; KEGG: mem:Memar_1082 GHMP kinase; SPTR: GHMP kinase.
       0.539
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
    0.420
EJG06275.1
TM2 domain-containing protein; PFAM: TM2 domain; KEGG: mpi:Mpet_2113 TM2 domain-containing protein; SPTR: TM2 domain containing protein.
       0.407
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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