STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Experiments
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[Homology]
Score
EJG07637.1Cobalamin (vitamin B12) biosynthesis CbiX protein; PFAM: CbiX; COGs: COG2138 conserved hypothetical protein; InterPro IPR002762; KEGG: mem:Memar_1731 sirohydrochlorin cobaltochelatase; PFAM: Cobalamin (vitamin B12) biosynthesis CbiX; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiX protein. (134 aa)    
Predicted Functional Partners:
EJG06911.1
TIGRFAM: siroheme synthase, N-terminal domain; COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367; KEGG: mem:Memar_0979 siroheme synthase; SPTR: Siroheme synthase; TIGRFAM: Sirohaem synthase, N-terminal.
  
 
 0.999
cbiA-2
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
    
 0.999
EJG07466.1
PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase; COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878; KEGG: mpi:Mpet_1755 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.993
EJG07639.1
Methanogenesis marker 13 metalloprotein; PFAM: Nitrogenase component 1 type Oxidoreductase; TIGRFAM: putative methanogenesis marker 13 metalloprotein; COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR017675:IPR000510; KEGG: mem:Memar_1733 hypothetical protein; PFAM: Nitrogenase/oxidoreductase, component 1; SPTR: Putative uncharacterized protein; TIGRFAM: Putative methanogenesis marker 13 metalloprotein.
 
   
 0.970
EJG07638.1
Hypothetical protein; COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; KEGG: mem:Memar_1732 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.963
EJG06906.1
uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR006366; KEGG: mem:Memar_0984 uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Uroporphyrinogen-III C-methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; Belongs to the precorrin methyltransferase family.
 
 
 0.941
EJG07464.1
Cobalamin (vitamin B12) biosynthesis CbiG protein; PFAM: Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal; COGs: COG2073 Cobalamin biosynthesis protein CbiG; InterPro IPR002750; KEGG: mem:Memar_0511 cobalamin biosynthesis protein CbiG; PFAM: Cobalamin (vitamin B12) biosynthesis CbiG, core; SPTR: Cobalamin (Vitamin B12) biosynthesis CbiG protein.
 
  
 0.858
EJG07460.1
PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; COGs: COG2241 Precorrin-6B methylase 1; InterPro IPR012818:IPR000878; KEGG: mem:Memar_0515 cobalt-precorrin-6Y C(5)-methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-6Y C5,15-methyltransferase (Decarboxylating); TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core.
 
  
 0.837
EJG07467.1
Methyltransferase type 11; PFAM: Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR013216; KEGG: mem:Memar_0508 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Methyltransferase type 11; SPTR: Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit.
    
 0.834
EJG07636.1
Methanogenesis marker domain 9; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: TIM-barrel protein, putative; putative methanogenesis marker domain 9; COGs: COG4008 metal-binding transcription factor; InterPro IPR017671; KEGG: mem:Memar_1729 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Putative methanogenesis marker domain 9.
 
     0.826
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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