STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07685.1Protein of unknown function UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: mpi:Mpet_0789 hypothetical protein; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047. (138 aa)    
Predicted Functional Partners:
EJG07686.1
PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR012269:IPR000425; KEGG: afu:AF1426 glycerol uptake facilitator, MIP channel (GlpF); PFAM: Major intrinsic protein; SPTR: Probable aquaporin AqpM; TIGRFAM: Aquaporin.
       0.631
EJG07687.1
PFAM: Uncharacterized protein conserved in archaea (DUF2180); COGs: COG4855 conserved hypothetical protein; InterPro IPR017211; KEGG: mth:MTH102 hypothetical protein; PFAM: Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427; SPTR: Putative uncharacterized protein.
       0.631
EJG07688.1
Protein of unknown function DUF2193; PFAM: Uncharacterized protein conserved in archaea (DUF2193); COGs: COG4883 conserved hypothetical protein; InterPro IPR018694; KEGG: mtp:Mthe_1137 hypothetical protein; PFAM: Protein of unknown function DUF2193; SPTR: Putative uncharacterized protein.
       0.626
EJG06578.1
PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: mem:Memar_1816 geranyltranstransferase; PFAM: Polyprenyl synthetase; SPTR: Geranylgeranyl-diphosphate synthase / farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
    
 0.598
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
    
  0.530
EJG06610.1
Di-trans-poly-cis-decaprenylcistransferase; PFAM: Putative undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; COGs: COG0020 Undecaprenyl pyrophosphate synthase; InterPro IPR001441; KEGG: mem:Memar_1787 di-trans-poly-cis-decaprenylcistransferase; PFAM:Di-trans-poly-cis-decaprenylcistransferase-lik e; SPTR: Di-trans-poly-cis-decaprenylcistransferase.
    
  0.530
EJG08345.1
PFAM: Histone deacetylase domain; COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: mem:Memar_2236 histone deacetylase superfamily protein; PFAM: Histone deacetylase superfamily; SPTR: Histone deacetylase superfamily.
 
     0.460
EJG07715.1
Peptidase A24B, FlaK domain protein; PFAM: Archaeal Peptidase A24 C-terminus Type II; InterPro IPR009655; KEGG: mem:Memar_2005 peptidase A24A, prepilin type IV; PFAM: Peptidase A24B, preflagellin, C-terminal; SPTR: Peptidase A24A, prepilin type IV.
  
    0.437
lig
DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
       0.407
pyrB
PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase; InterPro IPR006132:IPR006131:IPR002082; KEGG: mem:Memar_1689 aspartate carbamoyltransferase catalytic subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carba [...]
       0.407
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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