STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfdAPrefoldin subunit alpha; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. (144 aa)    
Predicted Functional Partners:
pfdB
Prefoldin subunit beta; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
 0.993
rpl31e
PFAM: Ribosomal protein L31e; COGs: COG2097 Ribosomal protein L31E; HAMAP: 50S ribosomal protein L31e; InterPro IPR000054; KEGG: mem:Memar_1969 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; SPTR: 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
 
  
 0.969
EJG07748.1
PFAM: Double-stranded DNA-binding domain; COGs: COG2118 DNA-binding protein; HAMAP: DNA-binding protein; InterPro IPR002836; KEGG: mem:Memar_1972 hypothetical protein; PFAM: DNA-binding TFAR19-related protein; SPTR: DNA-binding protein Memar_1972; Belongs to the PDCD5 family.
 
   0.953
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
       0.947
EJG07989.1
PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: thermosome, various subunits, archaeal; COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR002423; KEGG: mpl:Mpal_2699 chaperonin Cpn60/TCP-1; PFAM: Chaperonin Cpn60/TCP-1; SPTR: Chaperonin Cpn60/TCP-1.
   
 
 0.940
EJG08286.1
Thermosome; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: thermosome, various subunits, archaeal; T-complex protein 1, eta subunit; COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR002423:IPR012714; KEGG: mem:Memar_2346 thermosome; PFAM: Chaperonin Cpn60/TCP-1; SPTR: Thermosome subunit; TIGRFAM: Thermosome, archaeal.
   
 
 0.940
srp54
Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
    0.936
pus10
Conserved hypothetical protein CHP01213; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
       0.931
rpl21e
PFAM: Ribosomal protein L21e; COGs: COG2139 Ribosomal protein L21E; HAMAP: 50S ribosomal protein L21e; InterPro IPR001147; KEGG: mpl:Mpal_0547 50S ribosomal protein L21e; PFAM: Ribosomal protein L21e; SPTR: 50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
  
    0.912
rpl39e
PFAM: Ribosomal L39 protein; HAMAP: 50S ribosomal protein L39e; InterPro IPR000077; KEGG: mbn:Mboo_1884 50S ribosomal protein L39e; PFAM: Ribosomal protein L39e; SPTR: 50S ribosomal protein L39e; manually curated; Belongs to the eukaryotic ribosomal protein eL39 family.
 
     0.902
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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