STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07761.1PFAM: Protein of unknown function, DUF655; COGs: COG1491 RNA-binding protein; InterPro IPR007003; KEGG: mem:Memar_1959 hypothetical protein; PFAM: Protein of unknown function DUF655; SPTR: Putative uncharacterized protein. (187 aa)    
Predicted Functional Partners:
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
     
 0.971
EJG07760.1
PFAM: RNA polymerase Rpb4; COGs: COG1460 conserved hypothetical protein; InterPro IPR005574; KEGG: mpl:Mpal_0548 RNA polymerase Rpb4; PFAM: RNA polymerase II, Rpb4; SPTR: RNA polymerase Rpb4.
     
 0.964
pus10
Conserved hypothetical protein CHP01213; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs.
 
   
 0.952
rpl21e
PFAM: Ribosomal protein L21e; COGs: COG2139 Ribosomal protein L21E; HAMAP: 50S ribosomal protein L21e; InterPro IPR001147; KEGG: mpl:Mpal_0547 50S ribosomal protein L21e; PFAM: Ribosomal protein L21e; SPTR: 50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
  
 0.904
rpl31e
PFAM: Ribosomal protein L31e; COGs: COG2097 Ribosomal protein L31E; HAMAP: 50S ribosomal protein L31e; InterPro IPR000054; KEGG: mem:Memar_1969 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; SPTR: 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
 
     0.886
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
     0.867
srp54
Signal recognition 54 kDa protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
     0.864
trmY
UPF0217 protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
       0.816
rpl39e
PFAM: Ribosomal L39 protein; HAMAP: 50S ribosomal protein L39e; InterPro IPR000077; KEGG: mbn:Mboo_1884 50S ribosomal protein L39e; PFAM: Ribosomal protein L39e; SPTR: 50S ribosomal protein L39e; manually curated; Belongs to the eukaryotic ribosomal protein eL39 family.
 
     0.790
pfdA
Prefoldin subunit alpha; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
       0.779
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.