STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07848.1ATP-grasp fold domain protein, DUF201-type; PFAM: ATP-grasp domain; COGs: COG1821 ATP-utilizing protein (ATP-grasp superfamily); InterPro IPR003806; KEGG: mpl:Mpal_0581 protein of unknown function DUF201; PFAM: ATP-grasp fold, DUF201-type; SPTR: Putative uncharacterized protein. (294 aa)    
Predicted Functional Partners:
EJG07847.1
TIGRFAM: probable H4MPT-linked C1 transfer pathway protein; COGs: COG1548 transcriptional regulator/sugar kinase; InterPro IPR002756; KEGG: mbn:Mboo_0921 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Tetrahydromethanopterin-linked C1 transfer pathway, putative.
 
  
 0.999
mfnA
L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
 
  
 0.986
EJG06251.1
PFAM: Amino acid kinase family; COGs: COG2054 Uncharacterized kinase related to aspartokinase uridylate kinase; InterPro IPR001048; KEGG: mpl:Mpal_2593 aspartate/glutamate/uridylate kinase; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: Aspartate/glutamate/uridylate kinase.
 
   
 0.871
EJG06815.1
PFAM: Histidine biosynthesis protein; TIGRFAM: hisA/hisF family protein; COGs: COG1411 Uncharacterized protein related to proFAR isomerase (HisA); InterPro IPR006062; KEGG: mpl:Mpal_2062 histidine biosynthesis protein; PFAM: Histidine biosynthesis; SPTR: Histidine biosynthesis protein; manually curated.
 
     0.815
mfnB
UPF0264 protein; Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).
 
   
 0.801
EJG05994.1
TIGRFAM: dihydropteroate synthase-related protein; InterPro IPR000489:IPR005236; KEGG: mbn:Mboo_0215 dihydropteroate synthase-related protein; PFAM: Dihydropteroate synthase, DHPS; SPTR: Dihydropteroate synthase-related protein; TIGRFAM: Dihydropteroate synthase-related protein synthase-related protein.
  
   
 0.767
EJG06472.1
PFAM: Amidohydrolase family; TIGRFAM: formylmethanofuran dehydrogenase subunit A; COGs: COG1229 Formylmethanofuran dehydrogenase subunit A; InterPro IPR012027:IPR013108; KEGG: mem:Memar_0619 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: Formylmethanofuran dehydrogenase, subunit A; TIGRFAM: Formylmethanofuran dehydrogenase, subunit A.
 
   
 0.759
EJG06961.1
PFAM: Amidohydrolase family; TIGRFAM: formylmethanofuran dehydrogenase subunit A; COGs: COG1229 Formylmethanofuran dehydrogenase subunit A; InterPro IPR013108:IPR012027; KEGG: mem:Memar_1188 amidohydrolase 3; PFAM: Amidohydrolase 3; SPTR: Formylmethanofuran dehydrogenase, subunit A; TIGRFAM: Formylmethanofuran dehydrogenase, subunit A.
 
   
 0.755
ftr
formylmethanofuran/tetrahydromethanopterinN-form yltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
 
     0.740
EJG06471.1
PFAM: GXGXG motif; TIGRFAM: formylmethanofuran dehydrogenase subunit C; COGs: COG2218 Formylmethanofuran dehydrogenase subunit C; InterPro IPR017550:IPR002489; KEGG: mem:Memar_0618 formylmethanofuran dehydrogenase; PFAM: Glutamate synthase, alpha subunit, C-terminal; SPTR: Formylmethanofuran dehydrogenase, subunit C; TIGRFAM: Formylmethanofuran dehydrogenase subunit C.
  
     0.726
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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