STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07870.1PFAM: 4Fe-4S binding domain; COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR001450; KEGG: rci:RRC203 2(4Fe-4S) ferredoxin-domain-containing protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 2(4Fe-4S) ferredoxin-domain protein. (369 aa)    
Predicted Functional Partners:
EJG07486.1
PFAM: Uncharacterized membrane protein (DUF2298); TIGRFAM: Chlor_Arch_YYY domain; COGs: COG5427 Uncharacterized membrane protein; InterPro IPR018746; KEGG: mem:Memar_0722 hypothetical protein; PFAM: YYY membrane protein; SPTR: Putative uncharacterized protein; TIGRFAM: YYY membrane protein.
   
    0.857
EJG06497.1
Sucraseferredoxin family protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; COGs: COG3411 Ferredoxin; InterPro IPR009737; KEGG: mpl:Mpal_0554 ferredoxin, 2Fe-2S; PFAM: Sucraseferredoxin-like; SPTR: Ferredoxin, 2Fe-2S.
    
 0.717
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.636
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.630
EJG06013.1
Methanogenesis marker 16 metalloprotein; PFAM: Domain of unknown function DUF39; TIGRFAM: putative methanogenesis marker 16 metalloprotein; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708:IPR001450:IPR017677; KEGG: mem:Memar_0110 hypothetical protein; PFAM: Protein of unknown function DUF39; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein; TIGRFAM: Putative methanogenesis marker 16 metalloprotein.
 
  
  0.617
EJG08110.1
PFAM: Conserved region in glutamate synthase; COGs: COG0069 Glutamate synthase domain 2; KEGG: mpi:Mpet_1273 ferredoxin-dependent glutamate synthase; SPTR: Ferredoxin-dependent glutamate synthase.
  
  
  0.599
EJG08020.1
PFAM: Pyridine nucleotide-disulphide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027; KEGG: mbn:Mboo_2329 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
  0.595
EJG06001.1
PFAM: 4Fe-4S binding domain; Domain of unknown function (DUF362); COGs: COG2006 conserved hypothetical protein; InterPro IPR007160:IPR001450; KEGG: mem:Memar_0366 hypothetical protein; PFAM: Protein of unknown function DUF362; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: Putative uncharacterized protein.
 
     0.580
EJG07053.1
PFAM: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family; COGs: COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase gamma subunit; InterPro IPR019752; KEGG: mem:Memar_0842 pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit.
 
 
  0.570
EJG07492.1
Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase; COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: mem:Memar_0715 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase.
 
  
  0.565
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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