STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07886.1KEGG: mpi:Mpet_1774 hypothetical protein; SPTR: Putative uncharacterized protein. (229 aa)    
Predicted Functional Partners:
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
     
 0.954
EJG07884.1
Histone acetyltransferase, ELP3 family; PFAM: Acetyltransferase (GNAT) family; Radical SAM superfamily; TIGRFAM: histone acetyltransferase, ELP3 family; COGs: COG1243 Histone acetyltransferase; InterPro IPR006638:IPR005910:IPR007197:IPR000182; KEGG: mla:Mlab_1304 hypothetical protein; PFAM: Radical SAM; GCN5-related N-acetyltransferase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Histone acetyltransferase, ELP3 family; TIGRFAM: Histone acetyltransferase ELP3.
       0.944
EJG07883.1
Protein of unknown function UPF0058; PFAM: Uncharacterised protein family UPF0058; InterPro IPR002753; KEGG: mhu:Mhun_1134 hypothetical protein; PFAM: Uncharacterised protein family UPF0058; SPTR: Putative uncharacterized protein.
  
    0.940
polB
Metallophosphoesterase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
    
 
 0.913
EJG06684.1
Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667:IPR003156; KEGG: mem:Memar_1684 phosphoesterase, DHHA1; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Phosphoesterase, DHHA1.
    
 
 0.887
EJG08157.1
PFAM: DHH family; DHHA1 domain; COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667:IPR003156; KEGG: mem:Memar_0429 phosphoesterase domain-containing protein; PFAM: Phosphoesterase, DHHA1; Phosphoesterase, RecJ-like; SPTR: Phosphoesterase, RecJ domain protein.
    
 
 0.887
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
  
    0.842
rps27e
PFAM: Ribosomal protein S27; COGs: COG2051 Ribosomal protein S27E; HAMAP: 30S ribosomal protein S27e; InterPro IPR000592; KEGG: mpl:Mpal_0956 30S ribosomal protein S27e; PFAM: Ribosomal protein S27e; SPTR: 30S ribosomal protein S27e.
       0.828
EJG07889.1
PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain; COGs: COG1093 Translation initiation factor 2 alpha subunit (eIF-2alpha); InterPro IPR003029:IPR011488; KEGG: mem:Memar_2051 translation initiation factor IF-2 subunit alpha; PFAM: Eukaryotic translation initiation factor 2, alpha subunit; Ribosomal protein S1, RNA binding domain; SPTR: Translation initiation factor 2 subunit alpha (AeIF-2a).
       0.807
EJG07891.1
PFAM: PAC2 family; TIGRFAM: TIGR00162 family protein; COGs: COG2047 conserved hypothetical protein (ATP-grasp superfamily); InterPro IPR004426:IPR002766; KEGG: mpi:Mpet_1769 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP00062.
       0.575
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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