STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
nop10Ribosome biogenesis protein Nop10; Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA. (53 aa)    
Predicted Functional Partners:
truB
rRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.
   
 0.999
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
   
 0.999
EJG08036.1
Hypothetical protein; PFAM: Gar1/Naf1 RNA binding region; KEGG: mpl:Mpal_0332 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated.
   
 0.999
EJG07889.1
PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain; COGs: COG1093 Translation initiation factor 2 alpha subunit (eIF-2alpha); InterPro IPR003029:IPR011488; KEGG: mem:Memar_2051 translation initiation factor IF-2 subunit alpha; PFAM: Eukaryotic translation initiation factor 2, alpha subunit; Ribosomal protein S1, RNA binding domain; SPTR: Translation initiation factor 2 subunit alpha (AeIF-2a).
  
  
 0.948
EJG06228.1
PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; COGs: COG1761 DNA-directed RNA polymerase subunit L; InterPro IPR011261; KEGG: mpl:Mpal_2581 RNA polymerase dimerisation; PFAM: DNA-directed RNA polymerase, dimerisation; SPTR: RNA polymerase dimerisation.
  
    0.929
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
     
 0.792
EJG06125.1
PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein; COGs: COG1094 RNA-binding protein (contains KH domains); InterPro IPR004087:IPR018111:IPR019964; KEGG: mpl:Mpal_2793 putative RNA-processing protein; SMART: K Homology; SPTR: KH type 1 domain protein; TIGRFAM: KH domain protein, archaea.
   
 
 0.760
rps14
Ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles.
   
  
 0.754
rpoN
DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
   
    0.743
rpoP
DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
    0.704
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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