Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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[Homology]
Score
EJG07907.1PFAM: SPFH domain / Band 7 family; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: mpl:Mpal_0970 band 7 protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Band 7 protein. (358 aa)    
Predicted Functional Partners:
EJG07908.1
Protein of unknown function DUF107; PFAM: NfeD-like; InterPro IPR002810; KEGG: mem:Memar_0501 hypothetical protein; PFAM: Nodulation efficiency, NfeD; SPTR: Putative uncharacterized protein.
 
 
 0.984
EJG06601.1
Small GTP-binding protein; PFAM: GTPase of unknown function; COGs: COG0486 GTPase; InterPro IPR002917:IPR005225; KEGG: mpl:Mpal_2664 small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein.
   
 0.911
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 0.687
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
 
  0.679
EJG07165.1
26S proteasome subunit P45 family; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: 26S proteasome subunit P45 family; COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterPro IPR003959:IPR005937:IPR003593; KEGG: mem:Memar_1308 proteasome-activating nucleotidase; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: Proteasome-activating nucleotidase; TIGRFAM: 26S proteasome subunit P45.
   
 
 0.643
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
   
 
 0.643
EJG07132.1
ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR004014:IPR008250:IPR005834:IPR006068:IPR 001757; KEGG: tcx:Tcr_1065 ATPase, E1-E2 type; PFAM: ATPase, P-type, ATPase-associated region; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; SPTR [...]
   
 0.632
EJG07325.1
ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR004014:IPR008250:IPR005834:IPR 006068; KEGG: mma:MM_0901 cation-transporting ATPase; PFAM: ATPase, P-type, ATPase-associated region; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-termina [...]
   
 0.632
EJG07995.1
Peptidase S16, Lon-like protease; PFAM: Magnesium chelatase, subunit ChlI; Sigma-54 interaction domain; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related putative ATP-dependent protease; COGs: COG1067 ATP-dependent protease; InterPro IPR003593:IPR004663:IPR000523:IPR008269; KEGG: mem:Memar_0276 ATP-dependent protease Lon; PFAM: Peptidase S16, lon C-terminal; Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Lon-B peptidase, Serine peptidase, MEROPS family S16; TIGRFAM: Peptidase S16, archaeal lon homologs; Belongs to the peptidase S16 family.
  
 
 0.619
EJG07713.1
PFAM: Type II/IV secretion system protein; PIN domain; COGs: COG1855 ATPase (PilT family); InterPro IPR002716:IPR006596:IPR003593; KEGG: mem:Memar_2007 ATPase; PFAM: PilT protein, N-terminal; SMART: Nucleotide binding protein, PINc; ATPase, AAA+ type, core; SPTR: ATPase, PilT family.
      
 0.591
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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