STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07907.1PFAM: SPFH domain / Band 7 family; COGs: COG0330 Membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107; KEGG: mpl:Mpal_0970 band 7 protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Band 7 protein. (358 aa)    
Predicted Functional Partners:
EJG07908.1
Protein of unknown function DUF107; PFAM: NfeD-like; InterPro IPR002810; KEGG: mem:Memar_0501 hypothetical protein; PFAM: Nodulation efficiency, NfeD; SPTR: Putative uncharacterized protein.
 
  
 0.945
EJG06601.1
Small GTP-binding protein; PFAM: GTPase of unknown function; COGs: COG0486 GTPase; InterPro IPR002917:IPR005225; KEGG: mpl:Mpal_2664 small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: Small GTP-binding protein.
   
 0.935
EJG07165.1
26S proteasome subunit P45 family; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: 26S proteasome subunit P45 family; COGs: COG1222 ATP-dependent 26S proteasome regulatory subunit; InterPro IPR003959:IPR005937:IPR003593; KEGG: mem:Memar_1308 proteasome-activating nucleotidase; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: Proteasome-activating nucleotidase; TIGRFAM: 26S proteasome subunit P45.
   
 
 0.684
pan
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
   
 
 0.684
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 0.672
EJG07909.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR019734:IPR013105:IPR001440; KEGG: cyc:PCC7424_1361 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein.
   
 
 0.572
EJG06452.1
Pyrrolo-quinoline quinone repeat-containing protein; PFAM: PQQ enzyme repeat; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR002372:IPR018391; KEGG: mtp:Mthe_0878 cobaltochelatase; PFAM: Pyrrolo-quinoline quinone repeat; SPTR: Hypothetical secreted protein containing PQQ enzyme repeats.
 
 
 0.562
EJG07363.1
PFAM: AhpC/TSA family; COGs: COG1225 Peroxiredoxin; InterPro IPR000866; KEGG: tam:Theam_0591 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen.
 
   
 0.559
EJG07995.1
Peptidase S16, Lon-like protease; PFAM: Magnesium chelatase, subunit ChlI; Sigma-54 interaction domain; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related putative ATP-dependent protease; COGs: COG1067 ATP-dependent protease; InterPro IPR003593:IPR004663:IPR000523:IPR008269; KEGG: mem:Memar_0276 ATP-dependent protease Lon; PFAM: Peptidase S16, lon C-terminal; Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Lon-B peptidase, Serine peptidase, MEROPS family S16; TIGRFAM: Peptidase S16, archaeal lon homologs; Belongs to the peptidase S16 family.
  
 
 0.552
rps2
PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); COGs: COG0052 Ribosomal protein S2; InterPro IPR001865:IPR005707; KEGG: mbn:Mboo_2215 30S ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2P; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; Belongs to the universal ribosomal protein uS2 family.
   
 
 0.532
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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