STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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[Homology]
Score
EJG07916.1PFAM: Response regulator receiver domain; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789; KEGG: mbn:Mboo_1937 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein. (211 aa)    
Predicted Functional Partners:
EJG07695.1
PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: mpi:Mpet_1802 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SPTR: Multi-sensor signal transduction histidine kinase.
 
 0.840
EJG07775.1
PAS/PAC sensor hybrid histidine kinase; PFAM: HAMP domain; Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; CHASE4 domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG3322 periplasmic ligand-binding sensor domain; InterProIPR000014:IPR007892:IPR003660:IPR013767:IPR 003594:IPR001789:IPR001610; KEGG: mpi:Mpet_0061 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; CHASE4; HAMP linker domain; PAS fold; Signal transduction response regulator, receiver region; SMART: ATP-binding region, ATPase-like; PAS; HAMP linker dom [...]
 
 0.831
EJG08099.1
PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003018:IPR003594; KEGG: mem:Memar_1707 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; GAF; SMART: ATP-binding region, ATPase-like; GAF; SPTR: GAF sensor signal transduction histidine kinase.
 
 0.827
EJG07128.1
PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003594; KEGG: mem:Memar_2343 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; SMART: ATP-binding region, ATPase-like; HAMP linker domain; SPTR: Integral membrane sensor signal transduction histidine kinase.
 
 0.825
EJG07026.1
Multi-sensor signal transduction histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR013767:IPR013655:IPR013656:IPR 003594:IPR000014; KEGG: mpl:Mpal_1755 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; PAS fold; PAS fold-3; PAS fold-4; ATP-binding region, ATPase-like; SMART: Signal transduction res [...]
 
 0.817
EJG07915.1
Roadblock/LC7 family protein; PFAM: Roadblock/LC7 domain; InterPro IPR004942; KEGG: mpl:Mpal_2155 roadblock/LC7 family protein; PFAM: Dynein light chain-related; SPTR: Roadblock/LC7 family protein.
     
 0.815
EJG07340.1
Multi-sensor signal transduction histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR000014:IPR001789:IPR003594:IPR013656; KEGG: mhu:Mhun_2672 PAS/PAC sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; PAS fold-4; ATP-binding region, ATPase-like; SMART: Signal transduction response regulator, receiver region; PAS; A [...]
 
 0.812
EJG07351.1
PFAM: HAMP domain; Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003661:IPR003594:IPR004010; KEGG: mhu:Mhun_2689 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; Cache; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linke [...]
 
 0.806
EJG08159.1
Multi-sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR000014:IPR003018:IPR003594:IPR013767; KEGG: mem:Memar_0157 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; PAS fold; GAF; SMART: ATP-binding region, ATPase-like; PAS; GAF; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS.
 
 0.788
EJG07942.1
Multi-sensor signal transduction histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR000014:IPR001610:IPR003594:IPR 013656:IPR013767; KEGG: mpi:Mpet_0399 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; PAS fold-4; PAS fold; ATP-binding region, ATPase-like; SMART: Signal transduction response regula [...]
 
 0.787
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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