Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EJG07925.1PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; InterPro IPR004360; KEGG: mpi:Mpet_0484 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase/bleomycin resistance protein/dioxygenase. (162 aa)    
Predicted Functional Partners:
EJG06244.1
Rhodanese-like protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: mpi:Mpet_2048 rhodanese domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein.
   
 
 0.900
EJG06378.1
PFAM: Rhodanese-like domain; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: mem:Memar_2054 rhodanese domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein.
   
 
 0.900
EJG07396.1
Rhodanese-like protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: mem:Memar_2326 beta-lactamase domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Beta-lactamase domain protein.
   
 
 0.900
EJG06920.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR001450; KEGG: mpi:Mpet_1571 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
  
 
 0.833
EJG07563.1
4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S binding domain; COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR001450; KEGG: mbn:Mboo_0029 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
  
 
 0.833
EJG07926.1
KEGG: mba:Mbar_A2402 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.773
EJG07651.1
ThiJ/PfpI domain-containing protein; PFAM: DJ-1/PfpI family; InterPro IPR002818; KEGG: mpl:Mpal_2564 ThiJ/PfpI domain protein; PFAM: ThiJ/PfpI; SPTR: ThiJ/PfpI domain protein.
 
 
 0.722
EJG07905.1
Hypothetical protein; PFAM: DJ-1/PfpI family; KEGG: mhu:Mhun_1340 ThiJ/PfpI; SPTR: ThiJ/PfpI; manually curated.
 
 
 0.708
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.655
EJG07228.1
Class II aldolase/adducin family protein; PFAM: Class II Aldolase and Adducin N-terminal domain; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: mhu:Mhun_3173 L-fuculose phosphate aldolase; PFAM: Class II aldolase/adducin, N-terminal; SPTR: Class II aldolase/adducin-like protein.
 
 
 0.640
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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