Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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EJG07934.1Phosphoesterase PA-phosphatase related protein; PFAM: PAP2 superfamily; InterPro IPR000326; KEGG: atm:ANT_23660 phosphatase; PFAM: Phosphatidic acid phosphatase type 2/haloperoxidase; SMART: Phosphatidic acid phosphatase type 2/haloperoxidase; SPTR: Phosphatase. (330 aa)    
Predicted Functional Partners:
rpl6
Ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.
   
 0.904
EJG06344.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: mem:Memar_2154 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: AMP-dependent synthetase and ligase.
   
 0.881
EJG07672.1
AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme; COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: mpl:Mpal_1032 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: AMP-dependent synthetase and ligase.
   
 0.881
mfnA
L-tyrosine decarboxylase; Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis; Belongs to the group II decarboxylase family. MfnA subfamily.
    
 0.787
EJG06053.1
PFAM: ATP synthase (C/AC39) subunit; COGs: COG1527 H+-ATPase subunit C; InterPro IPR002843; KEGG: mhu:Mhun_1772 H+-transporting two-sector ATPase, C (AC39) subunit; PFAM: ATPase, V0/A0 complex, subunit C/D; SPTR: H+-transporting two-sector ATPase, C (AC39) subunit.
   
 
 0.764
atpC
V-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.764
atpF
V-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
   
 
 0.757
EJG07474.1
PFAM: Phosphatidylglycerophosphatase A; TIGRFAM: alpha-ribazole phosphatase CobZ; COGs: COG1267 Phosphatidylglycerophosphatase A and related protein; InterPro IPR007686; KEGG: mbn:Mboo_0702 phosphatidylglycerophosphatase A; PFAM: Phosphatidylglycerophosphatase A; SPTR: Phosphatidylglycerophosphatase A.
 
 
 0.741
EJG07341.1
PFAM: Glycerophosphoryl diester phosphodiesterase family; COGs: COG0584 Glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: mem:Memar_1359 glycerophosphoryl diester phosphodiesterase; PFAM: Glycerophosphoryl diester phosphodiesterase; SPTR: Glycerophosphoryl diester phosphodiesterase.
 
 0.737
EJG07933.1
Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: ter:Tery_2914 short chain dehydrogenase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR.
 
 
 0.725
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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