STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07936.1PFAM: Putative pyruvate format-lyase activating enzyme (DUF1786); COGs: COG4012 conserved hypothetical protein; InterPro IPR014846; KEGG: mem:Memar_0319 pyruvate formate-lyase activating enzyme; PFAM: Protein of unknown function DUF1786, putative pyruvate format-lyase activating enzyme; SPTR: Pyruvate formate-lyase activating enzyme. (343 aa)    
Predicted Functional Partners:
EJG07937.1
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833; KEGG: mem:Memar_0320 anaerobic ribonucleoside-triphosphate reductase; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic.
 
     0.814
EJG07938.1
Glutaredoxin; KEGG: mbn:Mboo_1708 glutaredoxin; SPTR: Glutaredoxin.
       0.774
EJG07935.1
Putative PAS/PAC sensor protein; PFAM: Response regulator receiver domain; PAS fold; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789:IPR013767; KEGG: mpl:Mpal_0573 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver region; PAS fold; SMART: Signal transduction response regulator, receiver region; SPTR: Response regulator receiver protein.
       0.529
EJG07939.1
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
       0.514
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
       0.514
EJG06545.1
PFAM: Uncharacterized protein conserved in archaea (DUF2117); COGs: COG4069 conserved hypothetical protein; InterPro IPR012032; KEGG: mem:Memar_1862 hypothetical protein; PFAM: Uncharacterised conserved protein UCP006598; SPTR: Putative uncharacterized protein.
  
     0.471
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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