STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EJG07939.12'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (182 aa)    
Predicted Functional Partners:
cca
CCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
 
   
 0.959
dacZ
Protein of unknown function DUF147; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
       0.699
EJG07593.1
PFAM: Protein of unknown function (DUF424); COGs: COG2412 conserved hypothetical protein; InterPro IPR007355; KEGG: mem:Memar_1239 hypothetical protein; PFAM: Protein of unknown function DUF424; SPTR: Putative uncharacterized protein.
       0.666
EJG08211.1
Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: mtp:Mthe_0750 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Phosphoribosyltransferase.
       0.654
EJG06109.1
Protein of unknown function DUF343; PFAM: Trm112p-like protein; InterPro IPR005651; KEGG: mem:Memar_0006 hypothetical protein; PFAM: Protein of unknown function DUF343; SPTR: Putative uncharacterized protein.
 
     0.630
EJG06834.1
Hypothetical protein; COGs: COG0237 Dephospho-CoA kinase; KEGG: mem:Memar_1556 hypothetical protein; SPTR: UPF0200 protein Memar_1556.
 
     0.622
EJG07941.1
KEGG: pat:Patl_1101 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.584
rpl39e
PFAM: Ribosomal L39 protein; HAMAP: 50S ribosomal protein L39e; InterPro IPR000077; KEGG: mbn:Mboo_1884 50S ribosomal protein L39e; PFAM: Ribosomal protein L39e; SPTR: 50S ribosomal protein L39e; manually curated; Belongs to the eukaryotic ribosomal protein eL39 family.
       0.569
rpl31e
PFAM: Ribosomal protein L31e; COGs: COG2097 Ribosomal protein L31E; HAMAP: 50S ribosomal protein L31e; InterPro IPR000054; KEGG: mem:Memar_1969 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; SPTR: 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
       0.569
eif6
Translation initiation factor 6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
       0.569
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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