STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ccaCCA-adding enzyme; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (465 aa)    
Predicted Functional Partners:
EJG07939.1
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
     0.953
EJG08172.1
UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901; KEGG: mem:Memar_1336 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: UBA/THIF-type NAD/FAD binding protein.
  
 
 0.949
nac
Nascent polypeptide-associated complex protein; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
 
     0.802
EJG06515.1
PFAM: tRNA intron endonuclease, N-terminal domain; tRNA intron endonuclease, catalytic C-terminal domain; TIGRFAM: tRNA intron endonuclease; COGs: COG1676 tRNA splicing endonuclease; InterPro IPR006676:IPR006678:IPR006677; KEGG: mem:Memar_0641 tRNA splicing endonuclease; PFAM: tRNA intron endonuclease, catalytic domain-like; tRNA intron endonuclease, N-terminal; SPTR: tRNA intron endonuclease; TIGRFAM: tRNA-intron endonuclease.
  
   
 0.765
dnaG
UPF0095 protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
   
 0.670
EJG07761.1
PFAM: Protein of unknown function, DUF655; COGs: COG1491 RNA-binding protein; InterPro IPR007003; KEGG: mem:Memar_1959 hypothetical protein; PFAM: Protein of unknown function DUF655; SPTR: Putative uncharacterized protein.
  
   
 0.660
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
     0.652
EJG07937.1
TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833; KEGG: mem:Memar_0320 anaerobic ribonucleoside-triphosphate reductase; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic.
 
     0.646
EJG06834.1
Hypothetical protein; COGs: COG0237 Dephospho-CoA kinase; KEGG: mem:Memar_1556 hypothetical protein; SPTR: UPF0200 protein Memar_1556.
 
     0.643
EJG06125.1
PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein; COGs: COG1094 RNA-binding protein (contains KH domains); InterPro IPR004087:IPR018111:IPR019964; KEGG: mpl:Mpal_2793 putative RNA-processing protein; SMART: K Homology; SPTR: KH type 1 domain protein; TIGRFAM: KH domain protein, archaea.
  
     0.590
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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