STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG07942.1Multi-sensor signal transduction histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR000014:IPR001610:IPR003594:IPR 013656:IPR013767; KEGG: mpi:Mpet_0399 multi-sensor signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; PAS fold-4; PAS fold; ATP-binding region, ATPase-like; SMART: Signal transduction response regula [...] (740 aa)    
Predicted Functional Partners:
EJG08393.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR013163:IPR003660:IPR004089; KEGG: mem:Memar_0239 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; Cache, type 2; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis sensory transducer.
  
  
 0.983
EJG08392.1
CheA signal transduction histidine kinase; PFAM: CheW-like domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; Hpt domain; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207:IPR003594:IPR002545:IPR001789; KEGG: mem:Memar_0238 CheA signal transduction histidine kinases; PFAM: Signal transduction response regulator, receiver region; CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: Signal transduction response regulator, recei [...]
  
  
  0.965
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.950
EJG07355.1
Protein serine/threonine phosphatase; PFAM: 5TMR of 5TMR-LYT; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932:IPR011620:IPR010822; KEGG: mem:Memar_2468 stage II sporulation E family protein; PFAM: Sporulation stage II, protein E C-terminal; Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region; SMART: Protein phosphatase 2C-related; SPTR: Stage II sporulation E family protein.
 
 
 0.948
EJG06183.1
PFAM: Cache domain; HAMP domain; Stage II sporulation protein E (SpoIIE); COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR001932:IPR004010:IPR010822; KEGG: mbn:Mboo_0643 stage II sporulation E family protein; PFAM: Sporulation stage II, protein E C-terminal; HAMP linker domain; Cache; SMART: Protein phosphatase 2C-related; HAMP linker domain; SPTR: Stage II sporulation E family protein.
  
 
 0.941
EJG07208.1
MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: mem:Memar_1545 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase, CheR-type; SMART: MCP methyltransferase, CheR-type; SPTR: Protein-glutamate O-methyltransferase.
   
 0.936
EJG06003.1
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: mpi:Mpet_0205 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: CheW protein.
     
 0.909
EJG08285.1
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: mpi:Mpet_1620 CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: CheW protein.
     
 0.909
EJG08394.1
PFAM: CheW-like domain; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: mem:Memar_0240 putative CheW protein; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: Putative CheW protein.
     
 0.909
EJG07216.1
Methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; PAS fold; TIGRFAM: PAS domain S-box; COGs: COG0840 Methyl-accepting chemotaxis protein; InterProIPR000014:IPR001610:IPR004089:IPR013655:IPR 013656; KEGG: mbn:Mboo_1578 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; PAS fold-3; PAS fold-4; SMART: Chemotaxis methyl-accepting receptor, signalling; PAS; PAC motif; SPTR: Methyl-accepting chemotaxis sensory transducer; TIGRFAM: PAS.
  
 
 0.897
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.