STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG08039.1Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB; COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: mem:Memar_0470 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB. (215 aa)    
Predicted Functional Partners:
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.961
EJG07217.1
PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: mbn:Mboo_1301 hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation HypD protein; SPTR: Hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein.
 
  
 0.961
EJG06877.1
PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF; COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109; KEGG: mbn:Mboo_1411 hydrogenase assembly chaperone HypC/HupF; PFAM: Hydrogenase expression/formation protein, HupF/HypC; SPTR: Hydrogenase assembly chaperone hypC/hupF; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC.
 
  
 0.907
EJG06012.1
PFAM: Putative Fe-S cluster; COGs: COG2000 Fe-S protein; InterPro IPR007202; KEGG: mem:Memar_0109 Fe-S cluster domain-containing protein; PFAM: Putative Fe-S cluster; SPTR: Fe-S cluster domain protein.
 
    0.879
EJG08148.1
(NiFe) hydrogenase maturation protein HypF; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF; COGs: COG0068 Hydrogenase maturation factor; InterPro IPR001792:IPR011125:IPR006070:IPR004421; KEGG: mem:Memar_0417 (NiFe) hydrogenase maturation protein HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type; SPTR: (NiFe) hydrogenase maturation protein HypF; TIGRFAM: Hydrogenase maturation factor, HypF-type.
 
   
 0.869
EJG06010.1
PFAM: ABC transporter; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: mem:Memar_0107 ABC transporter-related protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter-related protein.
  
  
 0.863
EJG06879.1
Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR000728:IPR010918:IPR011854; KEGG: mem:Memar_1022 hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein; SPTR: Hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE.
 
  
 0.831
EJG06220.1
PFAM: Nickel-dependent hydrogenase; TIGRFAM: coenzyme F420 hydrogenase, subunit alpha; COGs: COG3259 Coenzyme F420-reducing hydrogenase alpha subunit; InterPro IPR001501:IPR017682; KEGG: mem:Memar_2174 nickel-dependent hydrogenase, large subunit; PFAM: Nickel-dependent hydrogenase, large subunit; SPTR: Coenzyme F420-reducing hydrogenase, alpha subunit; TIGRFAM: Coenzyme F420 hydrogenase, subunit alpha; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.719
EJG08037.1
PFAM: PHP domain; RNase P subunit p30; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR003141:IPR004013; KEGG: mbn:Mboo_2310 hypothetical protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP C-terminal domain protein.
       0.706
srp19
Ribonucleoprotein complex SRP, Srp19 component; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.
       0.706
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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