STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
infBTranslation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (602 aa)    
Predicted Functional Partners:
rpl2
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.999
rps2
PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); COGs: COG0052 Ribosomal protein S2; InterPro IPR001865:IPR005707; KEGG: mbn:Mboo_2215 30S ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2P; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; Belongs to the universal ribosomal protein uS2 family.
 
 
 0.999
rps3
Ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
  
 
 0.998
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
  
 
 0.998
rpl15
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
 
 0.998
rps11
Ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
 
 
 0.998
rps4
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
 
 
 0.998
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
 
 0.998
rpl10e
PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L10.e; COGs: COG0197 Ribosomal protein L16/L10E; HAMAP: 50S ribosomal protein L10e; InterPro IPR016180; KEGG: mpl:Mpal_1074 50S ribosomal protein L10e; PFAM: Ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L10e; Belongs to the universal ribosomal protein uL16 family.
  
 
 0.997
rpl1
Ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
 
 0.997
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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