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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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mptEProtein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. (206 aa)    
Predicted Functional Partners:
mptD
Protein of unknown function DUF381; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family.
 
  
 0.991
EJG06567.1
Dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase; COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: mpl:Mpal_0743 dihydropteroate synthase; PFAM: Dihydropteroate synthase, DHPS; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase.
    
 0.962
EJG08075.1
PFAM: Radical SAM superfamily; COGs: COG1031 Fe-S oxidoreductase; InterPro IPR006638:IPR007197; KEGG: mbn:Mboo_2273 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein.
 
     0.957
EJG08073.1
PFAM: DHH family; DHHA1 domain; TrkA-N domain; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR003148:IPR001667:IPR003156; KEGG: mem:Memar_0397 TrkA domain-containing protein; PFAM: Regulator of K+ conductance, N-terminal; Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: TrkA-N domain protein.
       0.942
EJG06622.1
Beta-lactamase domain-containing protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: mem:Memar_1774 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein.
    
  0.941
EJG06319.1
Queuosine biosynthesis protein QueD; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: mem:Memar_2208 putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: Putative uncharacterized protein; TIGRFAM: queuosine biosynthesis protein QueD.
    
 0.921
EJG06333.1
Beta-lactamase domain-containing protein; PFAM: Metallo-beta-lactamase superfamily; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: mem:Memar_2194 beta-lactamase domain-containing protein; SPTR: Beta-lactamase domain protein; manually curated.
    
  0.856
EJG06866.1
PFAM: Domain of unknown function (DUF373); COGs: COG2237 membrane protein; InterPro IPR007254; KEGG: mem:Memar_1451 hypothetical protein; PFAM: Protein of unknown function DUF373; SPTR: Putative uncharacterized protein.
 
     0.847
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
 
   
 0.771
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
       0.757
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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