Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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secEPreprotein translocase subunit secE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (66 aa)    
Predicted Functional Partners:
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
 
  
 0.987
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 0.978
rpl11
Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
   0.974
rpl31e
PFAM: Ribosomal protein L31e; COGs: COG2097 Ribosomal protein L31E; HAMAP: 50S ribosomal protein L31e; InterPro IPR000054; KEGG: mem:Memar_1969 50S ribosomal protein L31e; PFAM: Ribosomal protein L31e; SPTR: 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
 
   0.970
dtdA
D-tyrosyl-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.
 
   
 0.969
rpl10
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
 
   0.954
rpl1
Ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
 
 0.952
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
  
   0.943
ftsZ-2
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
  
 0.937
rpl29
PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29; InterPro IPR001854; KEGG: mem:Memar_0571 ribosomal protein L29; PFAM: Ribosomal protein L29; SPTR: LSU ribosomal protein L29P; TIGRFAM: Ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
  
   0.932
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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