Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EJG08102.1PFAM: CBS domain; COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000644; KEGG: mem:Memar_0345 signal-transduction protein; PFAM: Cystathionine beta-synthase, core; SMART: Cystathionine beta-synthase, core; SPTR: Putative signal-transduction protein with CBS domains. (140 aa)    
Predicted Functional Partners:
rps13
Ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family.
  
 
 0.706
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
   
 
 0.686
rps2
PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein Sa(cytosolic)/S2(archaeal); COGs: COG0052 Ribosomal protein S2; InterPro IPR001865:IPR005707; KEGG: mbn:Mboo_2215 30S ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2P; TIGRFAM: Ribosomal protein S2, eukaryotic/archaeal; Belongs to the universal ribosomal protein uS2 family.
   
   0.686
rpl37e
50S ribosomal protein L37e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
  
 
 
 0.685
rps7
Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.682
rps27e
PFAM: Ribosomal protein S27; COGs: COG2051 Ribosomal protein S27E; HAMAP: 30S ribosomal protein S27e; InterPro IPR000592; KEGG: mpl:Mpal_0956 30S ribosomal protein S27e; PFAM: Ribosomal protein S27e; SPTR: 30S ribosomal protein S27e.
  
 
   0.679
rpl3
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.673
rpl15
Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
 
 
 0.673
rps9
PFAM: Ribosomal protein S9/S16; TIGRFAM: archaeal ribosomal protein S9P; COGs: COG0103 Ribosomal protein S9; InterPro IPR000754:IPR019958; KEGG: mpi:Mpet_0754 30S ribosomal protein S9P; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9P; TIGRFAM: Ribosomal protein S9, archaeal; Belongs to the universal ribosomal protein uS9 family.
   
   0.664
rpl13
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.662
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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