Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
EJG08124.1PFAM: ThiS family; TIGRFAM: MoaD family protein, archaeal; InterPro IPR003749:IPR010038; KEGG: mla:Mlab_0189 hypothetical protein; PFAM: ThiamineS; SPTR: MoaD family protein; TIGRFAM: MoaD, archaeal. (92 aa)    
Predicted Functional Partners:
EJG08173.1
PFAM: MoaE protein; COGs: COG0314 Molybdopterin converting factor large subunit; InterPro IPR003448; KEGG: mem:Memar_1334 molybdopterin biosynthesis MoaE; PFAM: Molybdopterin biosynthesis MoaE; SPTR: Molybdopterin synthase subunit MoaE.
  
 0.972
EJG07426.1
PFAM: Molybdopterin guanine dinucleotide synthesis protein B; MoaE protein; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB; COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; InterPro IPR004435:IPR003448; KEGG: mem:Memar_0756 molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: Molybdopterin-guanine dinucleotide biosynthesis MobB region; Molybdopterin biosynthesis MoaE; SPTR: Molybdopterin guanine dinucleotide biosynthesis accessory protein MobB / molybdopterin synthase subunit MoaE; TIGRFAM: Molybdopterin-guanine dinucleotide bios [...]
  
 0.970
EJG08172.1
UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR000594:IPR007901; KEGG: mem:Memar_1336 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: UBA/THIF-type NAD/FAD binding protein.
 
 0.947
moaC
Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.
  
 
 0.936
EJG08125.1
PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal domain; Aldehyde ferredoxin oxidoreductase, domains 2 & 3; COGs: COG2414 Aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: mla:Mlab_0187 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: Aldehyde ferredoxin oxidoreductase, C-terminal; Aldehyde ferredoxin oxidoreductase, N-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal; SPTR: Aldehyde ferredoxin oxidoreductase.
 
  
 0.852
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
 
 0.833
EJG06116.1
PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453:IPR020817; KEGG: mpl:Mpal_2796 molybdenum cofactor synthesis domain protein; PFAM: Molybdopterin binding; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: Molybdenum cofactor synthesis.
  
 
 0.818
EJG07839.1
Molybdate ABC transporter, ATPase subunit; PFAM: ABC transporter; TOBE domain; TIGRFAM: molybdenum-pterin binding domain; molybdenum ABC transporter, ATP-binding protein; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR011868:IPR003439:IPR005116; KEGG: mem:Memar_1882 ABC transporter-related protein; PFAM: ABC transporter-like; Transport-associated OB, type 1; SMART: ATPase, AAA+ type, core; SPTR: Tungstate/molybdate transport system ATP-binding protein; TIGRFAM: Molybdate ABC transporter, ATP-binding protein.
     
 0.699
EJG08082.1
Molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110:IPR001453:IPR005111:IPR020817; KEGG: mem:Memar_0406 molybdenum cofactor synthesis domain-containing protein; PFAM: MoeA, N-terminal region, domain I/II; Molybdopterin binding; MoeA, C-terminal, domain IV; SPTR: Molybdopterin molybdochelatase; TIGRFAM: Molybdenum cofactor synthesis; overlaps another CDS with [...]
  
 
 0.635
EJG08081.1
Molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110:IPR001453:IPR005111:IPR020817; KEGG: mem:Memar_0405 putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; PFAM: Molybdopterin binding; MoeA, N-terminal region, domain I/II; MoeA, C-terminal, domain IV; SPTR: Molybdopterin molybdochelatase; TIGRFAM: Molybdenum cof [...]
 
 
 0.610
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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