Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EJG08140.1PFAM: Bacterial regulatory protein, arsR family; InterPro IPR001845; KEGG: mem:Memar_0013 regulatory protein, ArsR; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family. (122 aa)    
Predicted Functional Partners:
EJG08132.1
Arsenical-resistance protein; PFAM: Sodium Bile acid symporter family; TIGRFAM: arsenical-resistance protein; COGs: COG0798 Arsenite efflux pump ACR3 and related permease; InterPro IPR002657:IPR004706; KEGG: dol:Dole_2882 arsenical-resistance protein; PFAM: Bile acid:sodium symporter; SPTR: Putative uncharacterized protein; TIGRFAM: Arsenical-resistance protein ACR3.
 
  
 0.681
EJG05993.1
Hypothetical protein; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; KEGG: mpl:Mpal_0311 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.666
EJG08129.1
PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin); COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: mpl:Mpal_2571 protein-tyrosine phosphatase, low molecular weight; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein-tyrosine phosphatase, low molecular weight.
 
  
 0.639
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.587
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
  0.573
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
     
  0.572
EJG08138.1
Protein of unknown function DUF318, transmembrane; PFAM: Predicted permease; COGs: COG0701 permease; InterPro IPR005524; KEGG: mem:Memar_0015 permease; PFAM: Protein of unknown function DUF318, transmembrane; SPTR: Permease.
 
  
 0.547
EJG08139.1
Hypothetical protein.
       0.513
EJG08135.1
Redox-active disulfide protein 2; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.
 
   
 0.453
EJG08137.1
Protein of unknown function DUF318, transmembrane; PFAM: Predicted permease; COGs: COG0701 permease; InterPro IPR005524; KEGG: mpi:Mpet_0354 permease; PFAM: Protein of unknown function DUF318, transmembrane; SPTR: Permease.
 
  
 0.452
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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