Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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EJG08188.1Tetratricopeptide TPR_1 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR019734:IPR001440; KEGG: mhu:Mhun_1922 tetratricopeptide TPR_2; PFAM: Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Tetratricopeptide TPR_2. (113 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 0.760
rpoD
DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 0.758
dnaK
Chaperone protein dnaK; Acts as a chaperone.
  
 0.743
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.737
EJG06840.1
InterPro IPR019734:IPR001440:IPR013105; KEGG: mpi:Mpet_2763 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: TPR repeat-containing protein.
  
     0.717
EJG06575.1
PFAM: WD domain, G-beta repeat; PEGA domain; COGs: COG2319 FOG: WD40 repeat; InterPro IPR019781:IPR013229:IPR001680:IPR018391; KEGG: shc:Shell_0491 serine/threonine protein kinase with WD40 repeats; PFAM: PEGA; WD40 repeat, subgroup; SPTR: Putative WD domain, G-beta repeat.
  
 0.699
rpoH
RNA polymerase Rpb5; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family.
   
 0.699
EJG07306.1
PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: mma:MM_2829 peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; SPTR: Peptidyl-prolyl cis-trans isomerase.
  
 
 0.698
EJG07909.1
Tetratricopeptide TPR_2 repeat-containing protein; PFAM: Tetratricopeptide repeat; InterPro IPR019734:IPR013105:IPR001440; KEGG: cyc:PCC7424_1361 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein.
  
     0.693
EJG07294.1
WD40 repeat-containing protein; PFAM: WD domain, G-beta repeat; COGs: COG2319 FOG: WD40 repeat; InterPro IPR001680:IPR018391:IPR019781; KEGG: mem:Memar_0794 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: Pyrrolo-quinoline quinone beta-propeller repeat; WD40 repeat; SPTR: WD-40 repeat-containing protein.
  
 0.692
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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