STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG08200.1PFAM: PPIC-type PPIASE domain; COGs: COG0760 Parvulin-like peptidyl-prolyl isomerase; InterPro IPR000297; KEGG: mla:Mlab_1314 hypothetical protein; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase. (92 aa)    
Predicted Functional Partners:
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
 0.999
EJG06452.1
Pyrrolo-quinoline quinone repeat-containing protein; PFAM: PQQ enzyme repeat; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR002372:IPR018391; KEGG: mtp:Mthe_0878 cobaltochelatase; PFAM: Pyrrolo-quinoline quinone repeat; SPTR: Hypothetical secreted protein containing PQQ enzyme repeats.
   
 
 0.850
EJG07306.1
PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: mma:MM_2829 peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; SPTR: Peptidyl-prolyl cis-trans isomerase.
  
 0.697
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
  
  
 0.641
EJG08081.1
Molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110:IPR001453:IPR005111:IPR020817; KEGG: mem:Memar_0405 putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; PFAM: Molybdopterin binding; MoeA, N-terminal region, domain I/II; MoeA, C-terminal, domain IV; SPTR: Molybdopterin molybdochelatase; TIGRFAM: Molybdenum cof [...]
  
 
 0.581
EJG08082.1
Molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110:IPR001453:IPR005111:IPR020817; KEGG: mem:Memar_0406 molybdenum cofactor synthesis domain-containing protein; PFAM: MoeA, N-terminal region, domain I/II; Molybdopterin binding; MoeA, C-terminal, domain IV; SPTR: Molybdopterin molybdochelatase; TIGRFAM: Molybdenum cofactor synthesis; overlaps another CDS with [...]
  
 
 0.581
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
  
 0.559
EJG08253.1
PFAM: Amino acid kinase family; ACT domain; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR002912:IPR005260:IPR001341; KEGG: mpl:Mpal_0401 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase region; Aspartate kinase, monofunctional class; Belongs to the aspartokinase family.
 
  
 0.555
EJG08357.1
PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR002637; KEGG: mpl:Mpal_0597 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; PFAM: Ham1-like protein; SPTR: Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; TIGRFAM: Ham1-like protein; Belongs to the HAM1 NTPase family.
  
   0.545
EJG06976.1
Ribonuclease III; PFAM: RNase3 domain; Double-stranded RNA binding motif; COGs: COG0571 dsRNA-specific ribonuclease; InterPro IPR000999:IPR001159; KEGG: mem:Memar_0367 ribonuclease III; PFAM: Ribonuclease III; Double-stranded RNA binding; SMART: Ribonuclease III; Double-stranded RNA binding; SPTR: RNAse III.
  
  
 0.540
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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