STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Coexpression
Experiments
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[Homology]
Score
EJG08222.1DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase; InterPro IPR002941; KEGG: mpl:Mpal_2731 methyltransferase DNA modification enzyme; PFAM: DNA methylase N-4/N-6; SPTR: Methyltransferase DNA modification enzyme. (409 aa)    
Predicted Functional Partners:
EJG08221.1
PFAM: Radical SAM superfamily; TIGRFAM: putative peptide-modifying radical SAM enzyme, AF0577 family; radical SAM additional 4Fe4S-binding domain; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: mbn:Mboo_0233 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein.
 
     0.675
EJG07054.1
PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit; COGs: COG0045 Succinyl-CoA synthetase beta subunit; InterPro IPR013650:IPR005811:IPR005809; KEGG: mbn:Mboo_0727 succinyl-CoA synthetase, beta subunit; PFAM: ATP-grasp fold, succinyl-CoA synthetase-type; ATP-citrate lyase/succinyl-CoA ligase; SPTR: Succinyl-CoA synthetase, beta subunit; TIGRFAM: Succinyl-CoA synthetase, beta subunit.
 
    0.580
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
    0.579
EJG07995.1
Peptidase S16, Lon-like protease; PFAM: Magnesium chelatase, subunit ChlI; Sigma-54 interaction domain; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related putative ATP-dependent protease; COGs: COG1067 ATP-dependent protease; InterPro IPR003593:IPR004663:IPR000523:IPR008269; KEGG: mem:Memar_0276 ATP-dependent protease Lon; PFAM: Peptidase S16, lon C-terminal; Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Lon-B peptidase, Serine peptidase, MEROPS family S16; TIGRFAM: Peptidase S16, archaeal lon homologs; Belongs to the peptidase S16 family.
     
 0.575
EJG06138.1
PFAM: D12 class N6 adenine-specific DNA methyltransferase; TIGRFAM: DNA adenine methylase (dam); COGs: COG0338 Site-specific DNA methylase; InterPro IPR012327:IPR012326; KEGG: mpi:Mpet_0189 DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; SPTR: DNA adenine methylase; TIGRFAM: DNA adenine methylase.
 
  
 0.557
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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