Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EJG08230.1PEGA domain protein; PFAM: Alpha-macro-globulin thiol-ester bond-forming region; A-macroglobulin complement component; PEGA domain; InterPro IPR002102:IPR019565:IPR013229; KEGG: hbo:Hbor_31320 CARDB domain-containing protein; PFAM: PEGA; Alpha-2-macroglobulin, thiol-ester bond-forming; Cellulosome anchoring protein, cohesin region; SPTR: CARDB domain-containing protein. (1282 aa)    
Predicted Functional Partners:
EJG08231.1
Peptidase S8 and S53 subtilisin kexin sedolisin; PFAM: Cohesin domain; CARDB; Subtilase family; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR000209:IPR002102; KEGG: afu:AF1653 alkaline serine protease (AprM); PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; Cellulosome anchoring protein, cohesin region; SPTR: Alkaline serine protease (AprM); Belongs to the peptidase S8 family.
 
     0.963
EJG08229.1
Hypothetical protein.
       0.773
EJG08228.1
KEGG: mem:Memar_2407 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.705
EJG07271.1
PFAM: Protein of unknown function DUF55; COGs: COG1673 conserved hypothetical protein; HAMAP: UPF0310 protein; InterPro IPR002740; KEGG: mem:Memar_1478 hypothetical protein; PFAM: Uncharacterised protein family UPF0310; SPTR: Putative uncharacterized protein; Belongs to the UPF0310 family.
  
     0.406
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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