STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG08306.1Ribonuclease II; PFAM: RNB domain; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; COGs: COG0557 Exoribonuclease R; InterPro IPR001900; KEGG: mpl:Mpal_1199 ribonuclease II; PFAM: Ribonuclease II/R; SPTR: Ribonuclease II. (486 aa)    
Predicted Functional Partners:
EJG06963.1
KEGG: mpi:Mpet_1203 hypothetical protein; SPTR: Putative uncharacterized protein.
   
 0.999
EJG06316.1
PFAM: NUDIX domain; InterPro IPR000086; KEGG: mpi:Mpet_0609 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: NUDIX hydrolase.
   
 0.996
rsmA
Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
 
 
 0.817
dnaK
Chaperone protein dnaK; Acts as a chaperone.
 
 
 0.793
EJG06125.1
PFAM: KH domain; TIGRFAM: arCOG04150 universal archaeal KH domain protein; COGs: COG1094 RNA-binding protein (contains KH domains); InterPro IPR004087:IPR018111:IPR019964; KEGG: mpl:Mpal_2793 putative RNA-processing protein; SMART: K Homology; SPTR: KH type 1 domain protein; TIGRFAM: KH domain protein, archaea.
   
 
 0.764
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
  
 
 0.757
rps15
PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15; COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR012606:IPR000589; KEGG: mpi:Mpet_2006 ribosomal S13S15 domain-containing protein; PFAM: Ribosomal protein S13/S15, N-terminal; Ribosomal protein S15; SPTR: 30S ribosomal protein S15P/S13e.
  
 
 0.729
EJG06393.1
PFAM: Putative snoRNA binding domain; COGs: COG1498 Protein implicated in ribosomal biogenesis Nop56p homolog; InterPro IPR002687; KEGG: mem:Memar_0541 pre-mRNA processing ribonucleoprotein, binding region; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; SPTR: rRNA biogenesis protein Nop56/Nop58.
   
 
 0.713
rps9
PFAM: Ribosomal protein S9/S16; TIGRFAM: archaeal ribosomal protein S9P; COGs: COG0103 Ribosomal protein S9; InterPro IPR000754:IPR019958; KEGG: mpi:Mpet_0754 30S ribosomal protein S9P; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9P; TIGRFAM: Ribosomal protein S9, archaeal; Belongs to the universal ribosomal protein uS9 family.
 
  0.711
EJG06834.1
Hypothetical protein; COGs: COG0237 Dephospho-CoA kinase; KEGG: mem:Memar_1556 hypothetical protein; SPTR: UPF0200 protein Memar_1556.
  
  
 0.709
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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