STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EJG08348.1Transcriptional regulator NikR, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (142 aa)    
Predicted Functional Partners:
EJG06308.1
Transcriptional modulator of MazE/toxin, MazF; PFAM: PemK-like protein; COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: mem:Memar_1105 transcriptional modulator of MazE/toxin, MazF; PFAM: PemK-like protein; SPTR: Transcriptional modulator of MazE/toxin, MazF.
  
 
 0.980
eif2g
Translation initiation factor 2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
     
 0.588
EJG08350.1
Nucleotide binding protein PINc; PFAM: Fcf1; COGs: COG1412 Uncharacterized protein of PilT N-term./Vapc superfamily; InterPro IPR006596; KEGG: mem:Memar_2241 nucleotide binding protein, PINc; SMART: Nucleotide binding protein, PINc; SPTR: SSU processome protein Utp24.
 
     0.557
EJG08037.1
PFAM: PHP domain; RNase P subunit p30; COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR003141:IPR004013; KEGG: mbn:Mboo_2310 hypothetical protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: PHP C-terminal domain protein.
 
     0.540
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
     
 0.535
EJG06097.1
PFAM: ABC transporter; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: mem:Memar_0815 ABC transporter-related protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter-related protein.
     
 0.526
EJG06096.1
ABC-type transporter, integral membrane subunit; PFAM: ABC 3 transport family; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: mem:Memar_0814 ABC-3 protein; PFAM: ABC-3; SPTR: ABC-3 protein.
     
 0.517
spt4
DNA-directed RNA polymerase subunit E, RpoE2; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
     
 0.512
EJG06879.1
Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE; COGs: COG0309 Hydrogenase maturation factor; InterPro IPR000728:IPR010918:IPR011854; KEGG: mem:Memar_1022 hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein; SPTR: Hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE.
 
     0.499
EJG07052.1
Thiamine pyrophosphate TPP-binding domain-containing protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: mem:Memar_0843 thiamine pyrophosphate binding domain-containing protein; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; SPTR: 2-oxoglutarate ferredoxin oxidoreductase, beta subunit.
     
 0.499
Your Current Organism:
Methanofollis liminatans
NCBI taxonomy Id: 28892
Other names: M. liminatans DSM 4140, Methanofollis liminatans DSM 4140, Methanofollis liminatans GKZPZ, Methanofollis liminatans str. DSM 4140, Methanofollis liminatans strain DSM 4140, Methanogenium liminatans (DSM 4140), Methanogenium liminatans DSM 4140
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