node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARE79928.1 | infB | CHELV3228_0274 | CHELV3228_0275 | Putative nucleic-acid-binding protein (DUF448 domain); Pfam match to PF04296.11 DUF448. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.966 |
ARE79928.1 | thrB | CHELV3228_0274 | CHELV3228_0273 | Putative nucleic-acid-binding protein (DUF448 domain); Pfam match to PF04296.11 DUF448. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.800 |
ARE79928.1 | tsaB | CHELV3228_0274 | CHELV3228_0272 | Putative nucleic-acid-binding protein (DUF448 domain); Pfam match to PF04296.11 DUF448. | N6-L-threonylcarbamoyladenine synthase, TsaB subunit. | 0.795 |
hom | ilvE | CHELV3228_1492 | CHELV3228_1634 | Pfam matches to PF00742.17 Homoserine_dh, and to PF03447.14 NAD_binding_3, and to PF01842.23 ACT. | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.862 |
hom | luxS | CHELV3228_1492 | CHELV3228_0188 | Pfam matches to PF00742.17 Homoserine_dh, and to PF03447.14 NAD_binding_3, and to PF01842.23 ACT. | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.813 |
hom | metC | CHELV3228_1492 | CHELV3228_0885 | Pfam matches to PF00742.17 Homoserine_dh, and to PF03447.14 NAD_binding_3, and to PF01842.23 ACT. | Cystathionine-beta-lyase; Pfam match to PF01053.18 Cys_Met_Meta_PP. | 0.908 |
hom | metE | CHELV3228_1492 | CHELV3228_0187 | Pfam matches to PF00742.17 Homoserine_dh, and to PF03447.14 NAD_binding_3, and to PF01842.23 ACT. | Cobalamin-independent homocysteine transmethylase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.892 |
hom | thrB | CHELV3228_1492 | CHELV3228_0273 | Pfam matches to PF00742.17 Homoserine_dh, and to PF03447.14 NAD_binding_3, and to PF01842.23 ACT. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.994 |
hom | thrC | CHELV3228_1492 | CHELV3228_1430 | Pfam matches to PF00742.17 Homoserine_dh, and to PF03447.14 NAD_binding_3, and to PF01842.23 ACT. | Threonine synthase; Pfam matches to PF00291.23 PALP, and to PF14821.4 Thr_synth_N. | 0.971 |
ilvE | hom | CHELV3228_1634 | CHELV3228_1492 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Pfam matches to PF00742.17 Homoserine_dh, and to PF03447.14 NAD_binding_3, and to PF01842.23 ACT. | 0.862 |
ilvE | thrB | CHELV3228_1634 | CHELV3228_0273 | Branched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.829 |
infB | ARE79928.1 | CHELV3228_0275 | CHELV3228_0274 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Putative nucleic-acid-binding protein (DUF448 domain); Pfam match to PF04296.11 DUF448. | 0.966 |
infB | thrB | CHELV3228_0275 | CHELV3228_0273 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.802 |
infB | tsaB | CHELV3228_0275 | CHELV3228_0272 | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | N6-L-threonylcarbamoyladenine synthase, TsaB subunit. | 0.795 |
luxS | hom | CHELV3228_0188 | CHELV3228_1492 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Pfam matches to PF00742.17 Homoserine_dh, and to PF03447.14 NAD_binding_3, and to PF01842.23 ACT. | 0.813 |
luxS | metC | CHELV3228_0188 | CHELV3228_0885 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Cystathionine-beta-lyase; Pfam match to PF01053.18 Cys_Met_Meta_PP. | 0.953 |
luxS | metE | CHELV3228_0188 | CHELV3228_0187 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Cobalamin-independent homocysteine transmethylase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.960 |
luxS | thrB | CHELV3228_0188 | CHELV3228_0273 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.800 |
metC | hom | CHELV3228_0885 | CHELV3228_1492 | Cystathionine-beta-lyase; Pfam match to PF01053.18 Cys_Met_Meta_PP. | Pfam matches to PF00742.17 Homoserine_dh, and to PF03447.14 NAD_binding_3, and to PF01842.23 ACT. | 0.908 |
metC | luxS | CHELV3228_0885 | CHELV3228_0188 | Cystathionine-beta-lyase; Pfam match to PF01053.18 Cys_Met_Meta_PP. | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.953 |