node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARE80628.1 | clpB | CHELV3228_1039 | CHELV3228_1560 | Plasmid segregation protein ParM. | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | 0.881 |
ARE80628.1 | dnaJ | CHELV3228_1039 | CHELV3228_0396 | Plasmid segregation protein ParM. | DnaK system heat shock co-chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | 0.871 |
ARE80628.1 | groEL | CHELV3228_1039 | CHELV3228_0784 | Plasmid segregation protein ParM. | 60 kD chaperonin (cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.857 |
ARE80628.1 | groES | CHELV3228_1039 | CHELV3228_0783 | Plasmid segregation protein ParM. | 10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.814 |
ARE80628.1 | grpE | CHELV3228_1039 | CHELV3228_1419 | Plasmid segregation protein ParM. | DnaK system nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Se [...] | 0.957 |
ARE80628.1 | hslU | CHELV3228_1039 | CHELV3228_0319 | Plasmid segregation protein ParM. | Heat shock protein HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | 0.562 |
ARE80628.1 | hslV | CHELV3228_1039 | CHELV3228_0318 | Plasmid segregation protein ParM. | Heat shock protein HslVU, ATP-dependent protease subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.462 |
ARE80628.1 | htpG | CHELV3228_1039 | CHELV3228_1568 | Plasmid segregation protein ParM. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.985 |
clpB | ARE80628.1 | CHELV3228_1560 | CHELV3228_1039 | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | Plasmid segregation protein ParM. | 0.881 |
clpB | dnaJ | CHELV3228_1560 | CHELV3228_0396 | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | DnaK system heat shock co-chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | 0.643 |
clpB | dnaK | CHELV3228_1560 | CHELV3228_1420 | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | DnaK system heat shock chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.909 |
clpB | groEL | CHELV3228_1560 | CHELV3228_0784 | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | 60 kD chaperonin (cpn60); Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.614 |
clpB | groES | CHELV3228_1560 | CHELV3228_0783 | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | 10 kD chaperonin (cpn10); Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.643 |
clpB | grpE | CHELV3228_1560 | CHELV3228_1419 | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | DnaK system nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Se [...] | 0.797 |
clpB | hslU | CHELV3228_1560 | CHELV3228_0319 | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | Heat shock protein HslVU, ATPase subunit; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. | 0.566 |
clpB | hslV | CHELV3228_1560 | CHELV3228_0318 | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | Heat shock protein HslVU, ATP-dependent protease subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.413 |
clpB | htpG | CHELV3228_1560 | CHELV3228_1568 | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.780 |
dnaJ | ARE80628.1 | CHELV3228_0396 | CHELV3228_1039 | DnaK system heat shock co-chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | Plasmid segregation protein ParM. | 0.871 |
dnaJ | clpB | CHELV3228_0396 | CHELV3228_1560 | DnaK system heat shock co-chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | ATP-dependent Clp protease, ATP-binding subunit; Pfam matches to PF07724.12 AAA_2, and to PF10431.7 ClpB_D2-small, and to PF00004.27 AAA, and to PF02861.18 Clp_N; Belongs to the ClpA/ClpB family. | 0.643 |
dnaJ | dnaK | CHELV3228_0396 | CHELV3228_1420 | DnaK system heat shock co-chaperone; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions be [...] | DnaK system heat shock chaperone; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.996 |