STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pheAChorismate mutase / prephenate dehydratase; Bifunctional; Pfam matches to PF00800.16 PDT, and to PF01817.19 CM_2. (353 aa)    
Predicted Functional Partners:
aspB
Aspartate aminotransferase, aminotransferase, classes I and II; Pfam match to PF00155.19 Aminotran_1_2.
 
 
 0.992
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.989
tyrA
Chorismate mutase / prephenate dehydrogenase; Bifunctional; Pfam match to PF02153.15 PDH.
 0.978
trpDG
Anthranilate phosphoribosyltransferase / anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 
 
 0.975
trpE
Anthranilate synthase component I; Pfam match to PF00425.16 Chorismate_bind.
 
 
 0.963
hisC
Histidinol-phosphate aminotransferase; Pfam match to PF00155.19 Aminotran_1_2; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.958
aroG
2-dehydro-3-deoxyphosphoheptonate aldolase (DAHP synthetase, class II); Pfam match to PF01474.14 DAHP_synth_2.
   
 
 0.950
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
  
 0.932
serC
Phosphohydroxythreonine aminotransferase / 3-phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
  
 0.925
flgI
Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
    
   0.906
Your Current Organism:
Campylobacter helveticus
NCBI taxonomy Id: 28898
Other names: ATCC 51209, C. helveticus, CCUG 30682, CIP 104877, LMG 12638, LMG 19528, LMG:12638, LMG:19528, NCTC 12470
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