node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
adk | apt | CHELV3228_0969 | CHELV3228_1247 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.943 |
adk | guaA | CHELV3228_0969 | CHELV3228_0390 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | GMP synthase (acetyltransferase domains); Catalyzes the synthesis of GMP from XMP. | 0.585 |
adk | guaB | CHELV3228_0969 | CHELV3228_0443 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.499 |
adk | purB | CHELV3228_0969 | CHELV3228_0036 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Pfam matches to PF00206.18 Lyase_1, and to PF10397.7 ADSL_C; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.933 |
adk | pyrH | CHELV3228_0969 | CHELV3228_0498 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.541 |
adk | surE | CHELV3228_0969 | CHELV3228_1403 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.921 |
apt | adk | CHELV3228_1247 | CHELV3228_0969 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.943 |
apt | guaA | CHELV3228_1247 | CHELV3228_0390 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (acetyltransferase domains); Catalyzes the synthesis of GMP from XMP. | 0.994 |
apt | guaB | CHELV3228_1247 | CHELV3228_0443 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.616 |
apt | purA | CHELV3228_1247 | CHELV3228_1734 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.501 |
apt | purB | CHELV3228_1247 | CHELV3228_0036 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Pfam matches to PF00206.18 Lyase_1, and to PF10397.7 ADSL_C; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.938 |
apt | purH | CHELV3228_1247 | CHELV3228_1138 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | AICAR transformylase / IMP cyclohydrolase; Bifunctional; Pfam matches to PF01808.16 AICARFT_IMPCHas, and to PF02142.20 MGS. | 0.960 |
apt | surE | CHELV3228_1247 | CHELV3228_1403 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Broad specificity 5'(3')-nucleotidase and polyphosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.914 |
guaA | adk | CHELV3228_0390 | CHELV3228_0969 | GMP synthase (acetyltransferase domains); Catalyzes the synthesis of GMP from XMP. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.585 |
guaA | apt | CHELV3228_0390 | CHELV3228_1247 | GMP synthase (acetyltransferase domains); Catalyzes the synthesis of GMP from XMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.994 |
guaA | guaB | CHELV3228_0390 | CHELV3228_0443 | GMP synthase (acetyltransferase domains); Catalyzes the synthesis of GMP from XMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purA | CHELV3228_0390 | CHELV3228_1734 | GMP synthase (acetyltransferase domains); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.877 |
guaA | purB | CHELV3228_0390 | CHELV3228_0036 | GMP synthase (acetyltransferase domains); Catalyzes the synthesis of GMP from XMP. | Pfam matches to PF00206.18 Lyase_1, and to PF10397.7 ADSL_C; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.848 |
guaA | purH | CHELV3228_0390 | CHELV3228_1138 | GMP synthase (acetyltransferase domains); Catalyzes the synthesis of GMP from XMP. | AICAR transformylase / IMP cyclohydrolase; Bifunctional; Pfam matches to PF01808.16 AICARFT_IMPCHas, and to PF02142.20 MGS. | 0.863 |
guaA | pyrF | CHELV3228_0390 | CHELV3228_1676 | GMP synthase (acetyltransferase domains); Catalyzes the synthesis of GMP from XMP. | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.560 |