node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARE79956.1 | def | CHELV3228_0302 | CHELV3228_0301 | Mg chelatase-related protein; Pfam matches to PF01078.19 Mg_chelatase, and to PF13541.4 ChlI, and to PF13335.4 Mg_chelatase_C. | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.823 |
ARE79956.1 | ruvC | CHELV3228_0302 | CHELV3228_1828 | Mg chelatase-related protein; Pfam matches to PF01078.19 Mg_chelatase, and to PF13541.4 ChlI, and to PF13335.4 Mg_chelatase_C. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.604 |
addA | dnaE | CHELV3228_1713 | CHELV3228_1800 | Exonuclease V, helicase AddA; Pfam matches to PF00580.19 UvrD-helicase, and to PF13361.4 UvrD_C, and to PF13361.4 UvrD_C, and to PF12705.5 PDDEXK_1; Belongs to the helicase family. UvrD subfamily. | DNA polymerase III, alpha subunit; Pfam matches to PF07733.10 DNA_pol3_alpha, and to PF02811.17 PHP, and to PF14579.4 HHH_6. | 0.598 |
addA | mfd | CHELV3228_1713 | CHELV3228_1294 | Exonuclease V, helicase AddA; Pfam matches to PF00580.19 UvrD-helicase, and to PF13361.4 UvrD_C, and to PF13361.4 UvrD_C, and to PF12705.5 PDDEXK_1; Belongs to the helicase family. UvrD subfamily. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.504 |
addA | polA | CHELV3228_1713 | CHELV3228_0393 | Exonuclease V, helicase AddA; Pfam matches to PF00580.19 UvrD-helicase, and to PF13361.4 UvrD_C, and to PF13361.4 UvrD_C, and to PF12705.5 PDDEXK_1; Belongs to the helicase family. UvrD subfamily. | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.614 |
addA | recA | CHELV3228_1713 | CHELV3228_0092 | Exonuclease V, helicase AddA; Pfam matches to PF00580.19 UvrD-helicase, and to PF13361.4 UvrD_C, and to PF13361.4 UvrD_C, and to PF12705.5 PDDEXK_1; Belongs to the helicase family. UvrD subfamily. | Recombinase; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.499 |
addA | recJ | CHELV3228_1713 | CHELV3228_1596 | Exonuclease V, helicase AddA; Pfam matches to PF00580.19 UvrD-helicase, and to PF13361.4 UvrD_C, and to PF13361.4 UvrD_C, and to PF12705.5 PDDEXK_1; Belongs to the helicase family. UvrD subfamily. | Single-stranded DNA-specific exonuclease; Pfam matches to PF01368.18 DHH, and to PF02272.17 DHHA1. | 0.446 |
addA | ruvC | CHELV3228_1713 | CHELV3228_1828 | Exonuclease V, helicase AddA; Pfam matches to PF00580.19 UvrD-helicase, and to PF13361.4 UvrD_C, and to PF13361.4 UvrD_C, and to PF12705.5 PDDEXK_1; Belongs to the helicase family. UvrD subfamily. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.480 |
def | ARE79956.1 | CHELV3228_0301 | CHELV3228_0302 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Mg chelatase-related protein; Pfam matches to PF01078.19 Mg_chelatase, and to PF13541.4 ChlI, and to PF13335.4 Mg_chelatase_C. | 0.823 |
def | ruvC | CHELV3228_0301 | CHELV3228_1828 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.507 |
dnaE | addA | CHELV3228_1800 | CHELV3228_1713 | DNA polymerase III, alpha subunit; Pfam matches to PF07733.10 DNA_pol3_alpha, and to PF02811.17 PHP, and to PF14579.4 HHH_6. | Exonuclease V, helicase AddA; Pfam matches to PF00580.19 UvrD-helicase, and to PF13361.4 UvrD_C, and to PF13361.4 UvrD_C, and to PF12705.5 PDDEXK_1; Belongs to the helicase family. UvrD subfamily. | 0.598 |
dnaE | polA | CHELV3228_1800 | CHELV3228_0393 | DNA polymerase III, alpha subunit; Pfam matches to PF07733.10 DNA_pol3_alpha, and to PF02811.17 PHP, and to PF14579.4 HHH_6. | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.594 |
dnaE | ruvC | CHELV3228_1800 | CHELV3228_1828 | DNA polymerase III, alpha subunit; Pfam matches to PF07733.10 DNA_pol3_alpha, and to PF02811.17 PHP, and to PF14579.4 HHH_6. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.436 |
mfd | addA | CHELV3228_1294 | CHELV3228_1713 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Exonuclease V, helicase AddA; Pfam matches to PF00580.19 UvrD-helicase, and to PF13361.4 UvrD_C, and to PF13361.4 UvrD_C, and to PF12705.5 PDDEXK_1; Belongs to the helicase family. UvrD subfamily. | 0.504 |
mfd | polA | CHELV3228_1294 | CHELV3228_0393 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.583 |
mfd | recJ | CHELV3228_1294 | CHELV3228_1596 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Single-stranded DNA-specific exonuclease; Pfam matches to PF01368.18 DHH, and to PF02272.17 DHHA1. | 0.579 |
mfd | ruvA | CHELV3228_1294 | CHELV3228_1455 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | RuvABC resolvasome, subunit RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.524 |
mfd | ruvB | CHELV3228_1294 | CHELV3228_1452 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | RuvABC resolvasome, subunit RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.527 |
mfd | ruvC | CHELV3228_1294 | CHELV3228_1828 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | RuvABC resolvasome, subunit RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.443 |
polA | addA | CHELV3228_0393 | CHELV3228_1713 | DNA polymerase I, 5' --> 3' polymerase, 5' --> 3' and 3' --> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Exonuclease V, helicase AddA; Pfam matches to PF00580.19 UvrD-helicase, and to PF13361.4 UvrD_C, and to PF13361.4 UvrD_C, and to PF12705.5 PDDEXK_1; Belongs to the helicase family. UvrD subfamily. | 0.614 |