STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaIAAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)    
Predicted Functional Partners:
AQU85567.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
 
 0.993
AQU85988.1
DNA replication protein DnaD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.868
AQU85989.1
dephospho-CoA kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.725
AQU85986.1
23S rRNA (uracil-5-)-methyltransferase RumA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
  
    0.657
yigZ
Proline dipeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.653
B0W43_00920
Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.650
AQU85985.1
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
AQU85984.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.527
AQU85458.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.514
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.495
Your Current Organism:
Mycoplasma bovis
NCBI taxonomy Id: 28903
Other names: ATCC 25523, Bovine serotype 5, DSM 22781, M. bovis, Mycoplasma agalactiae subsp. bovis, Mycoplasma agalactiae var. bovis, Mycoplasma bovimastitidis, Mycoplasmopsis bovis, NCTC 10131, strain Donetta, strain PG 45, strain PG45
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