STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFI89403.1Methionine biosynthesis protein MetW. (206 aa)    
Predicted Functional Partners:
metXS
Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
  
 0.998
SFI89422.1
Protein of unknown function.
      0.938
SFI22157.1
Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.
    
 0.880
SFI22110.1
HxxPF-repeated domain-containing protein.
   
 0.816
SFI22142.1
Amino acid adenylation domain-containing protein.
    
 0.806
SFI89437.1
XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.800
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.752
cysC
Adenylylsulfate kinase /sulfate adenylyltransferase subunit 1; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
 
 0.723
SFI22190.1
Amino acid adenylation domain-containing protein.
    
 0.683
SFJ27976.1
Sarcosine oxidase subunit alpha; Belongs to the GcvT family.
     
 0.663
Your Current Organism:
Pseudomonas argentinensis
NCBI taxonomy Id: 289370
Other names: CCUG 50743, CECT 7010, LMG 22563, LMG:22563, P. argentinensis, Pseudomonas argentinae, Pseudomonas argentinensis Peix et al. 2005, Pseudomonas sp. M7C2, strain CH01
Server load: low (18%) [HD]