STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaQDNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (250 aa)    
Predicted Functional Partners:
dnaX
DNA polymerase III, gamma subunit /DNA polymerase III, tau subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.987
SFI95358.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 0.986
dnaE2
Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
    
 0.975
SFI35023.1
DNA polymerase III, alpha subunit.
    
 0.975
rnhA
RNase HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
 
 0.965
SFI35638.1
DNA polymerase III, delta subunit.
    
 0.962
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
 
 0.832
SFI33489.1
DNA polymerase III, chi subunit.
 
 
 0.821
SFI22951.1
DNA polymerase III, delta prime subunit.
  
 0.779
rnhA-2
Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
 
 
 0.777
Your Current Organism:
Pseudomonas argentinensis
NCBI taxonomy Id: 289370
Other names: CCUG 50743, CECT 7010, LMG 22563, LMG:22563, P. argentinensis, Pseudomonas argentinae, Pseudomonas argentinensis Peix et al. 2005, Pseudomonas sp. M7C2, strain CH01
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