STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACI21542.1Conserved hypothetical protein. (923 aa)    
Predicted Functional Partners:
ACI21940.1
UvrD/REP helicase domain protein, putative; Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily.
 
   
 0.966
ppdK
Pyruvate, phosphate dikinase; Identified by match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828; Belongs to the PEP-utilizing enzyme family.
       0.636
cst1
CRISPR-associated CXXC_CXXC protein Cst1; Identified by match to protein family HMM TIGR01908.
  
     0.571
ACI22030.1
Oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992.
 
     0.487
ACI21115.1
Methyltransferase small domain family; Identified by match to protein family HMM PF01170; match to protein family HMM PF05175.
       0.459
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
     
 0.442
polA
DNA polymerase I, thermostable; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.429
ACI21648.1
ATP-dependent DNA helicase PcrA; Identified by match to protein family HMM PF00580.
   
   0.425
ACI21683.1
ATP-dependent DNA helicase PcrA; Identified by match to protein family HMM PF00580.
   
   0.425
cas5_2
CRISPR-associated protein Cas5; Identified by match to protein family HMM TIGR02593.
  
     0.423
Your Current Organism:
Thermodesulfovibrio yellowstonii
NCBI taxonomy Id: 289376
Other names: T. yellowstonii DSM 11347, Thermodesulfovibrio yellowstonii DSM 11347
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.