STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACI21293.1Putative zinc-binding protein; Identified by match to protein family HMM PF03884. (72 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.786
dapB2
Dihydrodipicolinate reductase; Identified by match to protein family HMM PF01113; match to protein family HMM PF05173; match to protein family HMM TIGR00036.
       0.773
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.764
ACI22100.1
ABC-2 type transporter superfamily; Identified by match to protein family HMM PF01061.
       0.558
ACI21524.1
ABC-type multidrug transport system, ATPase component; Identified by match to protein family HMM PF00005.
       0.558
ACI20360.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Identified by match to protein family HMM PF00317; match to protein family HMM PF02867; match to protein family HMM TIGR02504.
       0.558
ACI20319.1
Sensory transduction protein LytT; Identified by match to protein family HMM PF00072; match to protein family HMM PF04397.
       0.469
ACI20975.1
Sensor protein LytS; Identified by match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694.
       0.469
ACI20413.1
Flagellar hook-associated protein 2; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
  
     0.428
Your Current Organism:
Thermodesulfovibrio yellowstonii
NCBI taxonomy Id: 289376
Other names: T. yellowstonii DSM 11347, Thermodesulfovibrio yellowstonii DSM 11347
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