STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACI22199.1Glutamate synthase-related protein; Identified by match to protein family HMM PF01645. (527 aa)    
Predicted Functional Partners:
ACI21545.1
Pyridine nucleotide-disulfide oxidoreductase; Identified by match to protein family HMM PF00037; match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF01493; match to protein family HMM PF07992.
 
 
 0.993
ACI21208.1
Conserved hypothetical protein.
 
 
 0.680
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.552
ACI20749.1
Helix-turn-helix domain protein; Identified by match to protein family HMM PF01381; match to protein family HMM PF07883.
       0.500
ACI21956.1
NiFe hydrogenase gamma subunit; Identified by match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF08022.
     
 0.496
ACI21368.1
Hydrogenase.
       0.488
ACI21606.1
F420-non-reducing hydrogenase vhu subunit G; Identified by match to protein family HMM PF01058.
       0.488
ACI20226.1
Hydrogenase/sulfur reductase, alpha subunit; Identified by match to protein family HMM PF00374.
       0.488
ACI21698.1
Conserved hypothetical protein.
 
   
 0.480
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.470
Your Current Organism:
Thermodesulfovibrio yellowstonii
NCBI taxonomy Id: 289376
Other names: T. yellowstonii DSM 11347, Thermodesulfovibrio yellowstonii DSM 11347
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