STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rgyTopoisomerase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1166 aa)    
Predicted Functional Partners:
AIH03824.1
Circadian clock protein KaiC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.776
AIH03823.1
Bacterio-opsin activator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.726
AIH04044.1
Hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
  
     0.603
AIH04069.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.586
AIH04440.1
Fumarate hydratase; Catalyzes the reversible hydration of fumaric acid to yield I-malic acid; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.543
AIH04441.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.543
AIH04442.1
Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.543
AIH04439.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.535
AIH04130.1
Chromosome partitioning protein ParB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.511
AIH04444.1
Cytochrome C biogenesis protein ResC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.484
Your Current Organism:
Thermodesulfobacterium commune
NCBI taxonomy Id: 289377
Other names: T. commune DSM 2178, Thermodesulfobacterium commune DSM 2178
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.