STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MYO1Myosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity). (1260 aa)    
Predicted Functional Partners:
CMD1
Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
    
 0.928
KLLA0_C04774g
KLLA0C04774p.
   
 
 0.919
KLLA0_B06039g
KLLA0B06039p.
    
 
 0.866
KLLA0_F23848g
KLLA0F23848p.
   
 
 0.791
KLLA0_B03498g
KLLA0B03498p.
    
 
 0.764
KLLA0_F10439g
KLLA0F10439p.
    
 
 0.716
KLLA0_E16699g
KLLA0E16699p.
    
 
 0.674
KLLA0_F19778g
KLLA0F19778p.
   
  
 0.670
KLLA0_F12210g
KLLA0F12210p.
   
 
 0.641
KLLA0_C16115g
KLLA0C16115p.
   
 
 0.641
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
Server load: low (20%) [HD]