STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLLA0_E09527gAP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (696 aa)    
Predicted Functional Partners:
KLLA0_B12243g
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
   
 0.993
KLLA0_C03894g
KLLA0C03894p; Belongs to the adaptor complexes medium subunit family.
   
 0.992
KLLA0_B06545g
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.991
KLLA0_E06579g
AP-1 complex subunit gamma.
   
 0.954
KLLA0_F09911g
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.
   
 0.950
KLLA0_D14311g
KLLA0D14311p; Belongs to the adaptor complexes medium subunit family.
    
 0.944
KLLA0_F22814g
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 0.943
KLLA0_F25432g
KLLA0F25432p; Belongs to the adaptor complexes medium subunit family.
    
 0.906
KLLA0_F05225g
KLLA0F05225p; Belongs to the small GTPase superfamily. Arf family.
   
 0.881
KLLA0_F14619g
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.
    
 0.862
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.