STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COA3Cytochrome c oxidase assembly factor 3, mitochondrial; Required for assembly of cytochrome c oxidase (complex IV). (88 aa)    
Predicted Functional Partners:
KLLA0_D12430g
KLLA0D12430p.
   
 
 0.662
KLLA0_F10956g
KLLA0F10956p.
   
 
 0.648
KLLA0_D10417g
KLLA0D10417p.
    
 
 0.585
COX1
Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...]
    
 
 0.533
KLLA0_B11451g
SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.
    
 
 0.522
KLLA0_E23893g
KLLA0E23893p.
  
    0.401
KLLA0_F06963g
KLLA0F06963p; Belongs to the universal ribosomal protein uS19 family.
   
    0.400
Your Current Organism:
Kluyveromyces lactis
NCBI taxonomy Id: 284590
Other names: K. lactis NRRL Y-1140, Kluyveromyces lactis NRRL Y-1140
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.