STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KSV59774.1RNA polymerase subunit sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (211 aa)    
Predicted Functional Partners:
KSV59305.1
Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.826
KSV59950.1
Stage IV sporulation protein A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.771
KSV58358.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.769
KSV58342.1
Stage V sporulation protein AEB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.767
KSV58343.1
Stage V sporulation protein AD; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.767
KSV59306.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.766
KSV58708.1
Hypothetical protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
 
   
 0.764
spoIIAB
Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.761
KSV58079.1
Sporulation protein YabP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.760
gpr
Peptidase; Initiates the rapid degradation of small, acid-soluble proteins during spore germination; Belongs to the peptidase A25 family.
  
     0.753
Your Current Organism:
Acetivibrio ethanolgignens
NCBI taxonomy Id: 290052
Other names: A. ethanolgignens, ATCC 33324, Acetivibrio ethanoligignens, DSM 3005, LMG 7055, LMG:7055, strain 77-6
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